The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Id http://purl.obolibrary.org/obo/CHEBI_8673
http://purl.obolibrary.org/obo/CHEBI_8673
Preferred Name

pyrimethamine
Synonyms
Ethylpyrimidine
CD
5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine
pirimetamina
C12H13ClN4
Chloridyn
pyrimethamine
pyrimethaminum
Chloridine
5-(4'-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine
2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine
Diaminopyritamin
5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine
Primethamine
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Type http://www.w3.org/2002/07/owl#Class

All Properties

prefLabel
pyrimethamine
label
pyrimethamine
DBSynonym
diaminopyritamin
chloridin
pyremethamine
pirimetamin
pirimetamina
chloridine
ethylpyrimidine
pyrimethamine hcl
chloridyn
pyrimethamin
primethamine
cd
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ATCCode
P01BD01
Definition
An aminopyrimidine that is pyrimidine-2,4-diamine which is substituted at position 5 by a p-chlorophenyl group and at position 6 by an ethyl group. It is a folic acid antagonist used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
has effect
has pharmacological target
inhibits
type
has role
InChIKey
InChIKey=WKSAUQYGYAYLPV-UHFFFAOYSA-N
AHFScode
08:30.08
Synonym
Ethylpyrimidine
CD
5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine
pirimetamina
C12H13ClN4
Chloridyn
pyrimethamine
pyrimethaminum
Chloridine
5-(4'-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine
2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine
Diaminopyritamin
5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine
Primethamine
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xref
DrugBank:DB00205
BindingDB:18512
ChEBI:8673
KEGG DRUG:D00488
PharmGKB:PA451193
PubChem Compound:4993
CiteXplore:11313656
KEGG COMPOUND:C07391
PubChem Substance:46505987
Drugs.com:http://www.drugs.com/cdi/pyrimethamine.html
RxList:http://www.rxlist.com/cgi/generic/pyrime.htm
Wikipedia:Pyrimethamine
Beilstein:219864
CiteXplore:12543697
Wikipedia:http://en.wikipedia.org/wiki/Pyrimethamine
CiteXplore:19435820
ChemSpider:4819
CiteXplore:3377143
Reaxys:219864
CiteXplore:16157660
CiteXplore:11257045
NIST Chemistry WebBook:58-14-0
CASRN:58-14-0
PDB:CP6
National Drug Code Directory:0173-0201-55
Drugs Product Database (DPD):4774
ChEMBL:102080
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CASRN
58-14-0
prefixIRI
obo2:CHEBI_8673
SMILES
CCc1nc(N)nc(N)c1-c1ccc(Cl)cc1
CCC1=C(C(N)=NC(N)=N1)C1=CC=C(Cl)C=C1
may interact with
DBname
pyrimethamine
InChI
InChI=1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)
DBBrand
khloridin
pirimecidan
daraprim
tinduring
daraprime
malacid
malocid
darapram
fansidar
daraclor
maloprim
darachlor
tindurin
erbaprelina
disulone
malocide
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subClassOf
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