The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_8497 http://purl.obolibrary.org/obo/CHEBI_8497
Preferred Name	propoxyphene
Synonyms	(3R)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl propanoate C22H29NO2 1-benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propanoate
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	propoxyphene
label	propoxyphene
DBSynonym	dextropropoxyphene-m propoxyphene hcl dextroproxifeno d-propoxyphene dextropropoxyphene
ATCCode	N02AC74 N02AC04 N02AC54
Definition	A propanoate ester that has formula C22H29NO2.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000888 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0001273 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000443 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000476 http://purl.obolibrary.org/obo/OAE_0000632 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0000084 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001106 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000525 http://purl.obolibrary.org/obo/OAE_0000038 http://purl.obolibrary.org/obo/OAE_0001164 http://purl.obolibrary.org/obo/OAE_0000780 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0000491 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001035 http://purl.obolibrary.org/obo/OAE_0000246 http://purl.obolibrary.org/obo/OAE_0000402 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_0760 http://purl.obolibrary.org/obo/dinto_2787 http://purl.obolibrary.org/obo/dinto_3960
induces	http://purl.obolibrary.org/obo/dinto_1956
activates	http://purl.obolibrary.org/obo/dinto_0760 http://purl.obolibrary.org/obo/dinto_2787
inhibits	http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1221
type	http://www.w3.org/2002/07/owl#Class
has role	http://purl.obolibrary.org/obo/CHEBI_35480 http://purl.obolibrary.org/obo/CHEBI_51177 http://purl.obolibrary.org/obo/CHEBI_35482
InChIKey	InChIKey=XLMALTXPSGQGBX-ZZWBGTBQSA-N
is metabolised by	http://purl.obolibrary.org/obo/dinto_0901
blocks	http://purl.obolibrary.org/obo/dinto_3960
Synonym	(3R)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl propanoate C22H29NO2 1-benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propanoate
xref	PharmGKB:PA451142 ChEBI:8497 DrugBank:DB00647 ChEMBL:775741 Drugs.com:http://www.drugs.com/propoxyphene.html Patent:US2728779 RxList:http://www.rxlist.com/cgi/generic/propox.htm Beilstein:2167828 National Drug Code Directory:0378-7065-01 Wikipedia:http://en.wikipedia.org/wiki/Propoxyphene See more See less
CASRN	469-62-5
prefixIRI	obo2:CHEBI_8497
SMILES	CCC(=O)OC(Cc1ccccc1)([C@H](C)CN(C)C)c1ccccc1 CCC(=O)OC(CC1=CC=CC=C1)([C@H](C)CN(C)C)C1=CC=CC=C1
may interact with	http://purl.obolibrary.org/obo/CHEBI_127342 http://purl.obolibrary.org/obo/CHEBI_53766 http://purl.obolibrary.org/obo/CHEBI_3699 http://purl.obolibrary.org/obo/CHEBI_133809 http://purl.obolibrary.org/obo/dinto_DB00427 http://purl.obolibrary.org/obo/CHEBI_3387 http://purl.obolibrary.org/obo/CHEBI_10033 http://purl.obolibrary.org/obo/dinto_DB00752 http://purl.obolibrary.org/obo/CHEBI_4513 http://purl.obolibrary.org/obo/dinto_DB00503 http://purl.obolibrary.org/obo/dinto_DB00046 http://purl.obolibrary.org/obo/dinto_DB06274 See more See less
DBname	propoxyphene
InChI	InChI=1S/C22H29NO2/c1-5-21(24)25-22(18(2)17-23(3)4,20-14-10-7-11-15-20)16-19-12-8-6-9-13-19/h6-15,18H,5,16-17H2,1-4H3/t18-,22?/m1/s1
DBBrand	antalvic propacet propoxychel doloxen harmar propoxyphene hcl 65 doloxene erantin kesso-gesic depromic deprancol algafan prophene 65 dolene proxagesic darvon dolocap femadol See more See less
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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