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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_8382
http://purl.obolibrary.org/obo/CHEBI_8382
|
|---|---|
| Preferred Name | prednisone |
| Synonyms |
Dehydrocortisone
17,21-dihydroxypregna-1,4-diene-3,11,20-trione
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
prednisonum
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
prednisona
1,2-Dehydrocortisone
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
prednisone
C21H26O5
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | prednisone
|
|---|---|
| label | prednisone
|
| DBSynonym |
prednisonum [inn-latin]
prednisona [inn-spanish]
dehydrocortisone
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| ATCCode |
H02AB07
H02AB15
A07EA03
|
| Definition | A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
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| has effect |
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| has pharmacological target | |
| induces | |
| activates | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=XOFYZVNMUHMLCC-ZPOLXVRWSA-N
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| is metabolised by | |
| AHFScode | 68:04.00
|
| Synonym | Dehydrocortisone
17,21-dihydroxypregna-1,4-diene-3,11,20-trione
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
prednisonum
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
prednisona
1,2-Dehydrocortisone
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
prednisone
C21H26O5
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| xref |
Patent:US2579479
PubChem Substance:46508166
Patent:US2897216
KEGG COMPOUND:C07370
PubChem Compound:5865
Beilstein:2065301
CASRN:53-03-2
ChEMBL:127229
DrugBank:DB00635
Wikipedia:Prednisone
CiteXplore:18971570
ChEBI:8382
ChemSpider:5656
Wikipedia:http://en.wikipedia.org/wiki/Prednisone
National Drug Code Directory:0054-8739-25
CiteXplore:15859934
Drugs Product Database (DPD):868426
PharmGKB:PA451100
CiteXplore:23395281
RxList:http://www.rxlist.com/cgi/generic/pred.htm
CiteXplore:10438974
CiteXplore:23093541
Drugs.com:http://www.drugs.com/prednisone.html
Patent:US3134718
Patent:US2837464
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| CASRN | 53-03-2
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| prefixIRI | obo2:CHEBI_8382
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| is transported by | |
| is substrate of | |
| related with | |
| SMILES |
[H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)CC(=O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])C(=O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO
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| may interact with |
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| DBname | prednisone
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| InChI | InChI=1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
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| DBBrand |
delcortin
deltacortone
prednovister
dekortin
hostacortin
econosone
panasol
dacortin
winpred
retrocortine
juvason
encortone
pronison
colisone
nurison
rayos
delta-cortone
fiasone
deltacortisone
cartancyl
decortancyl
decortin
nisona
orasone
me-korti
dellacort a
cortancyl
ancortone
prednizon
delta-dome
parmenison
deltra
presone
sterapred
predeltin
prednisone intensol
bicortone
diadreson
cortidelt
enkorton
sone
deltacortene
prednicen-m
ultracortene
pehacort
incocortyl
paracort
betapar
in-sone
meticorten
wojtab
dacorten
metacortandracin
di-adreson
prednitone
dellacort
nizon
deltisone
apo-prednisone
cotone
prednicorm
encorton
novoprednisone
supercortil
prednilonga
prednidib
prednicot
delta e
zenadrid
ultracorten
adasone
precort
delta cortelan
origen prednisone
rectodelt
servisone
deltisona
panafcort
deltasone
lisacort
delta-cortelan
deltison
delta-cortisone
cortan
decortisyl
prednicort
prednison
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| subClassOf |
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