Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
Jump to:
| Id | http://purl.obolibrary.org/obo/CHEBI_8361
http://purl.obolibrary.org/obo/CHEBI_8361
|
|---|---|
| Preferred Name | pravastatin sodium |
| Synonyms |
(3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid
C23H35NaO7
sodium (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoate
C23H36O7
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
pravastatin sodium
|
|---|---|
| prefLabel |
pravastatin sodium
|
| is metabolised by | |
| is transported by |
See more
See less
|
| Definition |
An organic sodium salt that is the sodium salt of pravastatin. A reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA), it is used for lowering cholesterol and preventing cardiovascular disease. It is one of the lower potency statins, but has the advantage of fewer side effects compared with lovastatin and simvastatin.
|
| DBBrand |
vasten
pravaselect
mevalotin
selectin
pravachol
mevinolin
elisor
selipran
lipostat
oliprevin
See more
See less
|
| ATCCode |
C10AA03
|
| SMILES |
[Na+].[H][C@]12[C@H](C[C@H](O)C=C1C=C[C@H](C)[C@@H]2CC[C@@H](O)C[C@@H](O)CC([O-])=O)OC(=O)[C@@H](C)CC
[H][C@]12[C@H](C[C@H](O)C=C1C=C[C@H](C)[C@@H]2CC[C@@H](O)C[C@@H](O)CC(O)=O)OC(=O)[C@@H](C)CC
|
| InChI |
InChI=1S/C23H36O7.Na/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28;/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28);/q;+1/p-1/t13-,14-,16+,17+,18+,19-,20-,22-;/m0./s1
InChI=1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1
|
| CASRN |
81093-37-0
|
| prefixIRI |
obo2:CHEBI_8361
|
| Synonym |
(3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid
C23H35NaO7
sodium (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoate
C23H36O7
|
| has effect |
See more
See less
|
| binds |
See more
See less
|
| has role | |
| DBname |
pravastatin
|
| InChIKey |
InChIKey=VWBQYTRBTXKKOG-IYNICTALSA-M
InChIKey=TUZYXOIXSAXUGO-PZAWKZKUSA-N
|
| subClassOf | |
| may interact with |
See more
See less
|
| inhibits |
See more
See less
|
| related with | |
| is substrate of |
See more
See less
|
| type | |
| xref |
ChEMBL:130602
PubChem Substance:46504851
Wikipedia:http://en.wikipedia.org/wiki/Pravastatin
HMDB:HMDB05022
National Drug Code Directory:0003-5154-05
CiteXplore:1680649
Reaxys:4224939
KEGG DRUG:D00893
ChemSpider:49398
BindingDB:20688
CiteXplore:1926908
CiteXplore:1425808
RxList:http://www.rxlist.com/cgi/generic/pravast.htm
Drugs.com:http://www.drugs.com/cdi/pravastatin.html
Drugs Product Database (DPD):2247008
Wikipedia:Parvaststin
ChEBI:8361
PubChem Compound:54687
PharmGKB:PA451089
CASRN:81131-70-6
DrugBank:DB00175
See more
See less
|
| AHFScode |
24:06.08
|
| DBSalt |
pravastatin sodium
|
| has pharmacological target |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |