The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_8107 http://purl.obolibrary.org/obo/CHEBI_8107
Preferred Name	phenytoin
Synonyms	5,5-diphenyltetrahydro-1H-2,4-imidazoledione C15H12N2O2 5,5-Diphenyl-imidazolidine-2,4-dione DILANTIN 5,5-diphenylimidazolidine-2,4-dione PHENTYTOIN
Type	http://www.w3.org/2002/07/owl#Class

label	phenytoin
prefLabel	phenytoin
is metabolised by	http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1959 http://purl.obolibrary.org/obo/dinto_1221
is transported by	http://purl.obolibrary.org/obo/dinto_0887 http://purl.obolibrary.org/obo/dinto_1440
Definition	A imidazolidine-2,4-dione that consists of hydantoin bearing two phenyl substituents at position 5.
DBBrand	ekko ritmenal toin unicelles phenytoin-gerot epasmir 5 dantoinal danten di-phetine lehydan denyl diphenin epdantoin simple solantoin auranile idantoin phenatoine phanatine elepsindon novophenytoin epanutin difenin epihydan diphedal difetoin zentropil hidan mesantoin hidantina vitoria hidantal hydantol hidantomin lepitoin convul solantyl didan tdc 250 phenatine dilantin-125 phenhydanin oxylan dilantin acid ictalis simple epelin epinat phentytoin diphenylan antisacer ditoinate hidantina toin phenitoin comital difenilhidantoina phenhydan epilan idantoil sodanthon diphentyn epamin epised phenytex hydantin epdantoine simple gerot-epilan-d epilan d fenytoin dak difhydan thilophenyl prompt phenytoin sodium sodanton diphentoin diphantoin dihycon dillantin fenidantoin s hydantal dilabid zentronal epilantin saceril dantoinal klinos sinergina fenantoin epifenyl causoin silantin sylantoic phanantin citrullamon om hidantoina simple phentoin lepsin dantinal phenytoin awd solantin neosidantoina diphenat dilantin diphenine labopal hydantoinal hidantilo sanepil dintoin hidantina senosian enkelfel dantoine neos-hidantoina om-hydantoine eptal citrulliamon eptoin epilan-d iphenylhydantoin fentoin aleviatin diphedan novantoina comitoina tacosal di-hydan fenylepsin dintoina dilantine hindatal di-lan kessodanten minetoin hydantoin fenytoine sodantoin See more See less
ATCCode	N03AB02 N03AB04 N03AB05
SMILES	O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1 O=C1NC(=O)C(N1)(c1ccccc1)c1ccccc1
InChI	InChI=1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)
CASRN	57-41-0
prefixIRI	obo2:CHEBI_8107
altId	CHEBI:100921
Synonym	5,5-diphenyltetrahydro-1H-2,4-imidazoledione C15H12N2O2 5,5-Diphenyl-imidazolidine-2,4-dione DILANTIN 5,5-diphenylimidazolidine-2,4-dione PHENTYTOIN See more See less
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000447 http://purl.obolibrary.org/obo/OAE_0000395 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000597 http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000589 http://purl.obolibrary.org/obo/OAE_0000573 http://purl.obolibrary.org/obo/OAE_0000604 http://purl.obolibrary.org/obo/OAE_0000557 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000630 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000479 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0000617 http://purl.obolibrary.org/obo/OAE_0000650 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0000301 http://purl.obolibrary.org/obo/OAE_0001046 http://purl.obolibrary.org/obo/OAE_0000411 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0001489 http://purl.obolibrary.org/obo/OAE_0001449 http://purl.obolibrary.org/obo/OAE_0000801 http://purl.obolibrary.org/obo/OAE_0000567 http://purl.obolibrary.org/obo/OAE_0000549 http://purl.obolibrary.org/obo/OAE_0000545 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0001013 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000317 http://purl.obolibrary.org/obo/OAE_0000482 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000527 http://purl.obolibrary.org/obo/OAE_0000984 http://purl.obolibrary.org/obo/OAE_0000426 http://purl.obolibrary.org/obo/OAE_0000761 http://purl.obolibrary.org/obo/OAE_0000207 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0001538 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000539 http://purl.obolibrary.org/obo/OAE_0000169 http://purl.obolibrary.org/obo/OAE_0000612 http://purl.obolibrary.org/obo/OAE_0001055 http://purl.obolibrary.org/obo/OAE_0000454 http://purl.obolibrary.org/obo/OAE_0000632 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0001340 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001062 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0001101 http://purl.obolibrary.org/obo/OAE_0001420 http://purl.obolibrary.org/obo/OAE_0000671 http://purl.obolibrary.org/obo/OAE_0001050 http://purl.obolibrary.org/obo/OAE_0000419 http://purl.obolibrary.org/obo/OAE_0001295 http://purl.obolibrary.org/obo/OAE_0001308 http://purl.obolibrary.org/obo/OAE_0001070 http://purl.obolibrary.org/obo/OAE_0001068 http://purl.obolibrary.org/obo/OAE_0001529 http://purl.obolibrary.org/obo/OAE_0000309 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000586 http://purl.obolibrary.org/obo/OAE_0000772 http://purl.obolibrary.org/obo/OAE_0000494 http://purl.obolibrary.org/obo/OAE_0000510 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000842 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000666 http://purl.obolibrary.org/obo/OAE_0000433 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000674 http://purl.obolibrary.org/obo/OAE_0000473 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000525 http://purl.obolibrary.org/obo/OAE_0000968 http://purl.obolibrary.org/obo/OAE_0000438 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0001742 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000780 http://purl.obolibrary.org/obo/OAE_0001429 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000405 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000898 http://purl.obolibrary.org/obo/OAE_0000647 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0001336 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000491 http://purl.obolibrary.org/obo/OAE_0001305 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000421 http://purl.obolibrary.org/obo/OAE_0000516 http://purl.obolibrary.org/obo/OAE_0001147 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000470 http://purl.obolibrary.org/obo/OAE_0001291 http://purl.obolibrary.org/obo/OAE_0000501 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000462 http://purl.obolibrary.org/obo/OAE_0000618 http://purl.obolibrary.org/obo/OAE_0000513 http://purl.obolibrary.org/obo/OAE_0001364 http://purl.obolibrary.org/obo/OAE_0000350 See more See less
binds	http://purl.obolibrary.org/obo/dinto_1670 http://purl.obolibrary.org/obo/dinto_2667 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_1822 http://purl.obolibrary.org/obo/dinto_2679 http://purl.obolibrary.org/obo/dinto_0217 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1956 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_0465 http://purl.obolibrary.org/obo/dinto_1959 http://purl.obolibrary.org/obo/dinto_0887 http://purl.obolibrary.org/obo/dinto_1440 See more See less
has role	http://purl.obolibrary.org/obo/CHEBI_35623
DBname	phenytoin
InChIKey	InChIKey=CXOFVDLJLONNDW-UHFFFAOYSA-N
subClassOf	http://purl.obolibrary.org/obo/dinto_000055
may interact with	http://purl.obolibrary.org/obo/CHEBI_31348 http://purl.obolibrary.org/obo/dinto_DB00683 http://purl.obolibrary.org/obo/CHEBI_41879 http://purl.obolibrary.org/obo/CHEBI_6704 http://purl.obolibrary.org/obo/CHEBI_32250 http://purl.obolibrary.org/obo/dinto_DB01303 http://purl.obolibrary.org/obo/CHEBI_9948 http://purl.obolibrary.org/obo/CHEBI_7627 http://purl.obolibrary.org/obo/CHEBI_119573 http://purl.obolibrary.org/obo/CHEBI_585948 http://purl.obolibrary.org/obo/CHEBI_49960 http://purl.obolibrary.org/obo/CHEBI_49668 http://purl.obolibrary.org/obo/dinto_DB08864 http://purl.obolibrary.org/obo/CHEBI_68642 http://purl.obolibrary.org/obo/dinto_DB00822 http://purl.obolibrary.org/obo/CHEBI_28329 http://purl.obolibrary.org/obo/CHEBI_68621 http://purl.obolibrary.org/obo/CHEBI_66901 http://purl.obolibrary.org/obo/CHEBI_6715 http://purl.obolibrary.org/obo/CHEBI_4995 http://purl.obolibrary.org/obo/dinto_DB01384 http://purl.obolibrary.org/obo/CHEBI_44185 http://purl.obolibrary.org/obo/CHEBI_9939 http://purl.obolibrary.org/obo/CHEBI_3641 http://purl.obolibrary.org/obo/CHEBI_8707 http://purl.obolibrary.org/obo/dinto_DB00196 http://purl.obolibrary.org/obo/CHEBI_499361 http://purl.obolibrary.org/obo/dinto_DB04573 http://purl.obolibrary.org/obo/dinto_DB01223 http://purl.obolibrary.org/obo/dinto_DB04574 http://purl.obolibrary.org/obo/CHEBI_71253 http://purl.obolibrary.org/obo/CHEBI_4031 http://purl.obolibrary.org/obo/CHEBI_61049 http://purl.obolibrary.org/obo/dinto_DB01380 http://purl.obolibrary.org/obo/CHEBI_3752 http://purl.obolibrary.org/obo/CHEBI_3077 http://purl.obolibrary.org/obo/CHEBI_15765 http://purl.obolibrary.org/obo/dinto_DB01336 http://purl.obolibrary.org/obo/dinto_DB06287 http://purl.obolibrary.org/obo/dinto_DB01226 http://purl.obolibrary.org/obo/CHEBI_53766 http://purl.obolibrary.org/obo/CHEBI_3699 http://purl.obolibrary.org/obo/CHEBI_3611 http://purl.obolibrary.org/obo/dinto_DB01601 http://purl.obolibrary.org/obo/CHEBI_8382 http://purl.obolibrary.org/obo/CHEBI_133809 http://purl.obolibrary.org/obo/CHEBI_17650 http://purl.obolibrary.org/obo/CHEBI_66910 http://purl.obolibrary.org/obo/dinto_DB00364 http://purl.obolibrary.org/obo/CHEBI_18358 http://purl.obolibrary.org/obo/CHEBI_9331 http://purl.obolibrary.org/obo/CHEBI_17698 http://purl.obolibrary.org/obo/dinto_DB01167 http://purl.obolibrary.org/obo/dinto_DB00570 http://purl.obolibrary.org/obo/CHEBI_7824 http://purl.obolibrary.org/obo/CHEBI_50845 http://purl.obolibrary.org/obo/CHEBI_18243 http://purl.obolibrary.org/obo/dinto_DB01357 http://purl.obolibrary.org/obo/CHEBI_68584 http://purl.obolibrary.org/obo/CHEBI_3766 http://purl.obolibrary.org/obo/CHEBI_3761 http://purl.obolibrary.org/obo/dinto_DB01011 http://purl.obolibrary.org/obo/dinto_DB04572 http://purl.obolibrary.org/obo/CHEBI_75045 http://purl.obolibrary.org/obo/dinto_DB00290 http://purl.obolibrary.org/obo/CHEBI_59594 http://purl.obolibrary.org/obo/CHEBI_9654 http://purl.obolibrary.org/obo/dinto_DB00582 http://purl.obolibrary.org/obo/dinto_DB00427 http://purl.obolibrary.org/obo/CHEBI_6367 http://purl.obolibrary.org/obo/dinto_DB06212 http://purl.obolibrary.org/obo/dinto_DB00158 http://purl.obolibrary.org/obo/CHEBI_2611 http://purl.obolibrary.org/obo/CHEBI_63631 http://purl.obolibrary.org/obo/CHEBI_15367 http://purl.obolibrary.org/obo/CHEBI_6916 http://purl.obolibrary.org/obo/CHEBI_63637 http://purl.obolibrary.org/obo/dinto_DB08901 http://purl.obolibrary.org/obo/CHEBI_100241 http://purl.obolibrary.org/obo/CHEBI_5138 http://purl.obolibrary.org/obo/CHEBI_4728 http://purl.obolibrary.org/obo/CHEBI_49375 http://purl.obolibrary.org/obo/dinto_DB05773 http://purl.obolibrary.org/obo/CHEBI_3423 http://purl.obolibrary.org/obo/CHEBI_7907 http://purl.obolibrary.org/obo/CHEBI_6722 http://purl.obolibrary.org/obo/CHEBI_50885 http://purl.obolibrary.org/obo/CHEBI_71013 http://purl.obolibrary.org/obo/CHEBI_9774 http://purl.obolibrary.org/obo/CHEBI_3732 http://purl.obolibrary.org/obo/dinto_DB01058 http://purl.obolibrary.org/obo/CHEBI_6807 http://purl.obolibrary.org/obo/dinto_DB00684 http://purl.obolibrary.org/obo/CHEBI_64355 http://purl.obolibrary.org/obo/CHEBI_48574 http://purl.obolibrary.org/obo/CHEBI_41922 http://purl.obolibrary.org/obo/CHEBI_2914 http://purl.obolibrary.org/obo/dinto_DB00783 http://purl.obolibrary.org/obo/CHEBI_6888 http://purl.obolibrary.org/obo/dinto_DB00440 http://purl.obolibrary.org/obo/CHEBI_17263 http://purl.obolibrary.org/obo/CHEBI_10033 http://purl.obolibrary.org/obo/CHEBI_63628 http://purl.obolibrary.org/obo/dinto_DB04575 http://purl.obolibrary.org/obo/dinto_DB00286 http://purl.obolibrary.org/obo/CHEBI_9588 http://purl.obolibrary.org/obo/CHEBI_28593 http://purl.obolibrary.org/obo/CHEBI_9168 http://purl.obolibrary.org/obo/dinto_DB00762 http://purl.obolibrary.org/obo/CHEBI_9123 http://purl.obolibrary.org/obo/dinto_DB08866 http://purl.obolibrary.org/obo/dinto_DB01118 http://purl.obolibrary.org/obo/CHEBI_6950 http://purl.obolibrary.org/obo/dinto_DB03585 http://purl.obolibrary.org/obo/dinto_DB00977 http://purl.obolibrary.org/obo/CHEBI_4513 http://purl.obolibrary.org/obo/CHEBI_7772 http://purl.obolibrary.org/obo/CHEBI_6443 http://purl.obolibrary.org/obo/dinto_DB06201 http://purl.obolibrary.org/obo/CHEBI_73274 http://purl.obolibrary.org/obo/CHEBI_4495 http://purl.obolibrary.org/obo/CHEBI_49575 http://purl.obolibrary.org/obo/CHEBI_8378 http://purl.obolibrary.org/obo/dinto_DB00690 http://purl.obolibrary.org/obo/CHEBI_47426 http://purl.obolibrary.org/obo/CHEBI_63584 http://purl.obolibrary.org/obo/dinto_DB00401 http://purl.obolibrary.org/obo/CHEBI_42797 http://purl.obolibrary.org/obo/CHEBI_27899 http://purl.obolibrary.org/obo/CHEBI_4657 http://purl.obolibrary.org/obo/CHEBI_63638 http://purl.obolibrary.org/obo/CHEBI_28177 http://purl.obolibrary.org/obo/dinto_DB01114 http://purl.obolibrary.org/obo/CHEBI_27999 http://purl.obolibrary.org/obo/CHEBI_71418 http://purl.obolibrary.org/obo/CHEBI_28077 http://purl.obolibrary.org/obo/CHEBI_46345 http://purl.obolibrary.org/obo/CHEBI_9328 http://purl.obolibrary.org/obo/CHEBI_4707 http://purl.obolibrary.org/obo/CHEBI_68647 http://purl.obolibrary.org/obo/CHEBI_31355 http://purl.obolibrary.org/obo/CHEBI_9674 http://purl.obolibrary.org/obo/CHEBI_38940 http://purl.obolibrary.org/obo/dinto_DB00976 http://purl.obolibrary.org/obo/CHEBI_45783 http://purl.obolibrary.org/obo/dinto_DB00951 http://purl.obolibrary.org/obo/CHEBI_5118 See more See less
inhibits	http://purl.obolibrary.org/obo/dinto_1670 http://purl.obolibrary.org/obo/dinto_2667 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_1822 http://purl.obolibrary.org/obo/dinto_2679
related with	http://purl.obolibrary.org/obo/dinto_0217
induces	http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1956 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_0465 See more See less
is substrate of	http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1959 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_0887 http://purl.obolibrary.org/obo/dinto_1440 See more See less
type	http://www.w3.org/2002/07/owl#Class
xref	CiteXplore:7602118 Wikipedia:http://en.wikipedia.org/wiki/Phenytoin PubChem Substance:46508847 CASRN:57-41-0 Wikipedia:Phenytoin National Drug Code Directory:51672-4069-1 PubChem Compound:1775 PharmGKB:PA450947 ChemSpider:1710 Guide To Pharmacology:2624 KEGG DRUG:D00512 Drugs Product Database (DPD):780626 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/dil1136.shtml Beilstein:384532 ChEBI:8107 Drugs.com:http://www.drugs.com/cdi/phenytoin.html RxList:http://www.rxlist.com/cgi/generic/phenyt.htm IUPHAR:2624 KEGG COMPOUND:C07443 DrugBank:DB00252 See more See less
DBSynonym	phenytoine [inn-french] fenitoina [inn-spanish] 5,5-dwufenylohydantoina difenilhidantoina [spanish] phenytoine diphenylhydantoine [french] 5,5-diphenylhydantoin phenytoinum [inn-latin] diphenylhydatanoin phenytoin sodium diphenylhydantoin dihydantoin diphenylan sodium See more See less
AHFScode	28:12.12
DBSalt	phenytoin sodium
has pharmacological target	http://purl.obolibrary.org/obo/dinto_1670 http://purl.obolibrary.org/obo/dinto_2679

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