The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_8081 http://purl.obolibrary.org/obo/CHEBI_8081
Preferred Name	phentolamine
Synonyms	Phentolamine mesylate Regitine phentolaminum Rogitine fentolamina 3-[(4,5-dihydro-1H-imidazol-2-ylmethyl)(4-methylphenyl)amino]phenol Regitina 2-(N-(m-hydroxyphenyl)-p-toluidinomethyl)imidazoline phentolamine C17H19N3O
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	phentolamine
label	phentolamine
ATCCode	V03AB36 C04AB01
Definition	A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000335 http://purl.obolibrary.org/obo/OAE_0001249 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0001268 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000296 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000402 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_0234 http://purl.obolibrary.org/obo/dinto_1135
type	http://www.w3.org/2002/07/owl#Class
has role	http://purl.obolibrary.org/obo/CHEBI_35620 http://purl.obolibrary.org/obo/CHEBI_37890
InChIKey	InChIKey=MRBDMNSDAVCSSF-UHFFFAOYSA-N
blocks	http://purl.obolibrary.org/obo/dinto_0234 http://purl.obolibrary.org/obo/dinto_1135
AHFScode	12:16.00
Synonym	Phentolamine mesylate Regitine phentolaminum Rogitine fentolamina 3-[(4,5-dihydro-1H-imidazol-2-ylmethyl)(4-methylphenyl)amino]phenol Regitina 2-(N-(m-hydroxyphenyl)-p-toluidinomethyl)imidazoline phentolamine C17H19N3O See more See less
xref	Wikipedia:Phentolamine Drugs Product Database (DPD):2243737 PharmGKB:PA450926 BindingDB:50008789 National Drug Code Directory:0083-6830-02 CiteXplore:23926134 CiteXplore:23658874 Drugs.com:http://www.drugs.com/cons/phentolamine-injection.html DrugBank:DB00692 HMDB:HMDB14830 CiteXplore:23522530 CiteXplore:23666670 KEGG COMPOUND:C07439 IUPHAR:502 CASRN:50-60-2 ChemSpider:5571 RxList:http://www.rxlist.com/cgi/generic3/phentol.htm Patent:US2503059 Guide To Pharmacology:502 KEGG DRUG:D08362 ChEMBL:120131 PubChem Compound:5775 CiteXplore:23438114 CiteXplore:23887290 Reaxys:272944 PubChem Substance:46506535 Wikipedia:http://en.wikipedia.org/wiki/Phentolamine See more See less
CASRN	50-60-2
prefixIRI	obo2:CHEBI_8081
SMILES	CC1=CC=C(C=C1)N(CC1=NCCN1)C1=CC(O)=CC=C1 Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1
DBname	phentolamine
InChI	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)
DBBrand	rogitine regitipe phentolamine mesilate phentalamine phentolamine methanesulfonate regitine phentolamine methanesulphonate phentolamine mesylate [usan] regitin methanesulphonate regitin phenotolamine phentolamine mesylate regitine mesylate regitine methanesulfonate phentolamine, methyl sulfonate See more See less
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

Add comment

Add proposal

Subscribe to notes emails

Delete	Subject	Author	Type	Created
No notes to display