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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_7934
http://purl.obolibrary.org/obo/CHEBI_7934
|
|---|---|
| Preferred Name | paromomycin |
| Synonyms |
R-400
Zygomycin A1
paromomycinum
R 400
paucimycinum
estomycin
crestomycin
(1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside
PAROMOMYCIN
Monomycin A
Paromomycin
paucimycin
Catenulin
paromomicina
paromomycin
hydroxymycin
C23H45N5O14
paromomycine
Aminosidin
neomycin E
Hydroxymycin
(2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}-2-(hydroxymethyl)oxane-3,4-diol
aminosidine
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | paromomycin
|
|---|---|
| label | paromomycin
|
| DBSynonym |
aminosidin
paramomycin sulfate
aminosidine
|
| ATCCode | A07AA06
|
| Definition | An amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-alpha-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis.
|
| altId | CHEBI:44703
|
| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=UOZODPSAJZTQNH-LSWIJEOBSA-N
|
| AHFScode | 08:30.04
|
| Synonym | R-400
Zygomycin A1
paromomycinum
R 400
paucimycinum
estomycin
crestomycin
(1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside
PAROMOMYCIN
Monomycin A
Paromomycin
paucimycin
Catenulin
paromomicina
paromomycin
hydroxymycin
C23H45N5O14
paromomycine
Aminosidin
neomycin E
Hydroxymycin
(2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}-2-(hydroxymethyl)oxane-3,4-diol
aminosidine
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|
| xref |
CiteXplore:18947845
National Drug Code Directory:61570-529-10
Patent:US2895876
KEGG COMPOUND:C00832
Drugs.com:http://www.drugs.com/cdi/paromomycin.html
RxList:http://www.rxlist.com/cgi/generic/humatin.htm
PharmGKB:PA164784023
Drugs Product Database (DPD):2078759
ChemSpider:145115
CiteXplore:18447603
KEGG DRUG:D07467
Wikipedia:http://en.wikipedia.org/wiki/Paromomycin_sulfate
CASRN:7542-37-2
ChEMBL:425236
CiteXplore:8036682
PDBeChem:PAR
Reaxys:72285
PubChem Substance:46505391
DrugBank:DB01421
Patent:US2916485
PubChem Compound:165580
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| CASRN | 1263-89-4
|
| prefixIRI | obo2:CHEBI_7934
|
| SMILES | NC[C@@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)[C@H](N)[C@@H](O)[C@@H]1O
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| DBname | paromomycin
|
| InChI | InChI=1S/C23H45N5O14/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22/h5-23,29-36H,1-4,24-28H2/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1
|
| DBBrand | humatin
|
| subClassOf |
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