Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_75988
http://purl.obolibrary.org/obo/CHEBI_75988
|
|---|---|
| Preferred Name | teniposide |
| Synonyms |
C32H32O13S
HSDB 6546
teniposide
teniposidum
4'-Demethylepipodophyllotoxin-beta-D-thenylidene glucoside
VM-26
4'-Demethylepipodophyllotoxin 9-(4,6-O-2-thenylidene-beta-D-glucopyranoside)
(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-(2-thienylmethylene)-beta-D-glucopyranoside
NSC 122819
(10R,11R,15R,16S)-16-{[(4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-(thiophen-2-yl)-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9),2,7-trien-12-one
teniposido
NSC-122819
Vumon
See more
See less
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | teniposide
|
|---|---|
| label | teniposide
|
| DBSynonym |
teniposidum [inn-latin]
teniposido [inn-spanish]
|
| ATCCode | L01CB02
|
| Definition | A furonaphthodioxole that is a synthetic derivative of podophyllotoxin with anti-tumour activity; causes single- and double-stranded breaks in DNA and DNA-protein cross-links and prevents repair by topoisomerase II binding.
|
| altId | CHEBI:9917
|
| has effect |
See more
See less
|
| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=NRUKOCRGYNPUPR-PSZSYXFXSA-N
|
| is metabolised by | |
| AHFScode | 10:00.00
|
| Synonym | C32H32O13S
HSDB 6546
teniposide
teniposidum
4'-Demethylepipodophyllotoxin-beta-D-thenylidene glucoside
VM-26
4'-Demethylepipodophyllotoxin 9-(4,6-O-2-thenylidene-beta-D-glucopyranoside)
(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-(2-thienylmethylene)-beta-D-glucopyranoside
NSC 122819
(10R,11R,15R,16S)-16-{[(4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-(thiophen-2-yl)-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9),2,7-trien-12-one
teniposido
NSC-122819
Vumon
See more
See less
|
| xref |
DrugBank:DB00444
CASRN:29767-20-2
RxList:http://www.rxlist.com/cgi/generic2/teniposide.htm
CiteXplore:23466610
CiteXplore:21430063
Wikipedia:http://en.wikipedia.org/wiki/Teniposide
Drugs Product Database (DPD):588989
KEGG COMPOUND:C11153
KEGG DRUG:D02698
Drugs.com:http://www.drugs.com/cdi/teniposide.html
HMDB:HMDB14587
PubChem Substance:46507536
Wikipedia:Teniposide
Reaxys:1417328
CiteXplore:21821840
PubChem Compound:34698
PDBeChem:9TP
CiteXplore:22846410
ChemSpider:31930
CiteXplore:22644709
CiteXplore:23266449
PharmGKB:PA451611
National Drug Code Directory:0015-3075-19
CiteXplore:23679827
CiteXplore:23838380
See more
See less
|
| CASRN | 29767-20-2
|
| prefixIRI | obo2:CHEBI_75988
|
| is transported by | |
| SMILES | COc1cc(cc(OC)c1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3COC(O[C@H]3[C@H](O)[C@H]2O)c2cccs2)c2cc3OCOc3cc12
[H][C@]12COC(=O)[C@]1([H])[C@H](C1=CC(OC)=C(O)C(OC)=C1)C1=CC3=C(OCO3)C=C1[C@H]2O[C@@H]1O[C@]2([H])COC(O[C@@]2([H])[C@H](O)[C@H]1O)C1=CC=CS1
|
| DBname | teniposide
|
| InChI | InChI=1S/C32H32O13S/c1-37-19-6-13(7-20(38-2)25(19)33)23-14-8-17-18(42-12-41-17)9-15(14)28(16-10-39-30(36)24(16)23)44-32-27(35)26(34)29-21(43-32)11-40-31(45-29)22-4-3-5-46-22/h3-9,16,21,23-24,26-29,31-35H,10-12H2,1-2H3/t16-,21+,23+,24-,26+,27+,28+,29+,31?,32-/m0/s1
|
| DBBrand |
veham-sandoz
vumon
vee m-26
vehem
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |