The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_7582 http://purl.obolibrary.org/obo/CHEBI_7582
Preferred Name	nitrendipine
Synonyms	nitrendipine ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate 3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Bayotensin Nidrel nitrendipinum 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester Bylotensin C18H20N2O6 BAY e 5009 Baypress nitrendipino Deiten See more See less
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	nitrendipine
label	nitrendipine
DBSynonym	nitrendipinum [inn-latin] nitrendipino [inn-spanish] nitrendipin
ATCCode	C08CA08
Definition	A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension.
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2962 http://purl.obolibrary.org/obo/dinto_2965 http://purl.obolibrary.org/obo/dinto_3529 http://purl.obolibrary.org/obo/dinto_2979 http://purl.obolibrary.org/obo/dinto_3508 http://purl.obolibrary.org/obo/dinto_1027 See more See less
inhibits	http://purl.obolibrary.org/obo/dinto_2962 http://purl.obolibrary.org/obo/dinto_2965 http://purl.obolibrary.org/obo/dinto_3113 http://purl.obolibrary.org/obo/dinto_3529 http://purl.obolibrary.org/obo/dinto_2260 http://purl.obolibrary.org/obo/dinto_2979 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_3508 http://purl.obolibrary.org/obo/dinto_1027 See more See less
type	http://www.w3.org/2002/07/owl#Class
has role	http://purl.obolibrary.org/obo/CHEBI_35620 http://purl.obolibrary.org/obo/CHEBI_38215 http://purl.obolibrary.org/obo/CHEBI_35674
InChIKey	InChIKey=PVHUJELLJLJGLN-UHFFFAOYSA-N
is metabolised by	http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1956
Synonym	nitrendipine ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate 3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Bayotensin Nidrel nitrendipinum 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester Bylotensin C18H20N2O6 BAY e 5009 Baypress nitrendipino Deiten See more See less
xref	CASRN:39562-70-4 Wikipedia:Nitrendipine CiteXplore:20398559 NIST Chemistry WebBook:39562-70-4 Patent:CN101416954 Guide To Pharmacology:2334 Reaxys:498823 KEGG DRUG:D00629 ChemSpider:4351 Patent:US3799934 PharmGKB:PA146096020 Patent:DE2117571 CiteXplore:6085389 KEGG COMPOUND:C07713 IUPHAR:2334 PubChem Substance:46508817 Wikipedia:http://en.wikipedia.org/wiki/Nitrendipine DrugBank:DB01054 PubChem Compound:4507 BindingDB:50012016 CiteXplore:1725797 CiteXplore:1790544 CiteXplore:23648675 ChEMBL:553570 CiteXplore:21811924 HMDB:HMDB15187 See more See less
CASRN	39562-70-4
prefixIRI	obo2:CHEBI_7582
SMILES	CCOC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OC CCOC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC
DBname	nitrendipine
InChI	InChI=1S/C18H20N2O6/c1-5-26-18(22)15-11(3)19-10(2)14(17(21)25-4)16(15)12-7-6-8-13(9-12)20(23)24/h6-9,16,19H,5H2,1-4H3
DBBrand	baypress nitrepin bylotensin nidrel bayotensin deiten See more See less
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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