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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_7575
http://purl.obolibrary.org/obo/CHEBI_7575
|
|---|---|
| Preferred Name | nimodipine |
| Synonyms |
nimodipinum
C21H26N2O7
Nimodipine
3-(2-methoxyethyl) 5-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-beta-methoxyethyl ester 5-isopropyl ester
BAY e 9736
isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate
nimodipine
nimodipino
Periplum
Nimotop
2-methoxyethyl propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | nimodipine
|
|---|---|
| label | nimodipine
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| DBSynonym |
nimodipino [inn-spanish]
nimodipinum [inn-latin]
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| ATCCode | C08CA06
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| Definition | A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.
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| has effect |
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| has pharmacological target |
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| activates | |
| inhibits |
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| type | |
| has role | |
| InChIKey | InChIKey=UIAGMCDKSXEBJQ-UHFFFAOYSA-N
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| is metabolised by | |
| blocks | |
| AHFScode | 24:28.08
|
| Synonym | nimodipinum
C21H26N2O7
Nimodipine
3-(2-methoxyethyl) 5-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-beta-methoxyethyl ester 5-isopropyl ester
BAY e 9736
isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate
nimodipine
nimodipino
Periplum
Nimotop
2-methoxyethyl propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
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| xref |
PubChem Substance:46508497
CASRN:66085-59-4
KEGG DRUG:D00438
ChEMBL:465248
Drugs.com:http://www.drugs.com/cdi/nimodipine.html
BindingDB:50011690
ChEBI:7575
Reaxys:459792
DrugBank:DB00393
RxList:http://www.rxlist.com/cgi/generic2/nimodip.htm
CiteXplore:21869451
KEGG COMPOUND:C07267
CiteXplore:12137606
Patent:US3799934
CiteXplore:22262041
NIST Chemistry WebBook:66085-59-4
Patent:DE2117571
IUPHAR:2523
National Drug Code Directory:57664-135-64
Wikipedia:http://en.wikipedia.org/wiki/Nimodipine
CiteXplore:16180362
Drugs Product Database (DPD):2155923
CiteXplore:8519001
CiteXplore:22300914
PharmGKB:PA450633
PubChem Compound:4497
ChemSpider:4341
Wikipedia:Nimodipine
CiteXplore:17110283
Guide To Pharmacology:2523
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| CASRN | 66085-59-4
|
| prefixIRI | obo2:CHEBI_7575
|
| SMILES |
COCCOC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OC(C)C
COCCOC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC(C)C
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| may interact with |
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| DBname | nimodipine
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| InChI | InChI=1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3
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| DBBrand |
periplum
nimotop
nymalize
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| subClassOf |
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