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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_74274
http://purl.obolibrary.org/obo/CHEBI_74274
|
|---|---|
| Preferred Name | dextromoramide |
| Synonyms |
dextromoramida
palfium
SKF 5137
R 875
(3S)-3-methyl-4-(morpholin-4-yl)-2,2-diphenyl-1-(pyrrolidin-1-yl)butan-1-one
(+)-2,2-diphenyl-3-methyl-4-morpholinobutyrylpyrrolidine
3-methyl-4-(morpholin-4-yl)-2,2-diphenyl-1-(pyrrolidin-1-yl)butan-1-one
C25H32N2O2
SKF-5137
dextromoramidum
palphium
(+)-3-methyl-4-morpholino-2,2-diphenyl-1-(pyrrolidin-1-yl)butanone
dextromoramide
pyrrolamidolum
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | dextromoramide
|
|---|---|
| label | dextromoramide
|
| Definition | An N-acylpyrrolidine arising by formal condensation of pyrrolidine with (3S)-3-methyl-4-(morpholin-4-yl)-2,2-diphenylbutanoic acid. An opioid analgesic that is structurally related to methadone, it is more poweful than morphine but shorter acting. It has been used (particularly as the hydrogen tartrate salt) for the treatment of severe pain, but was discontinued in the UK in 2004.
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| type | |
| has role | |
| InChIKey |
InChIKey=INUNXTSAACVKJS-OAQYLSRUSA-N
InChIKey=INUNXTSAACVKJS-UHFFFAOYSA-N
|
| Synonym |
dextromoramida
palfium
SKF 5137
R 875
(3S)-3-methyl-4-(morpholin-4-yl)-2,2-diphenyl-1-(pyrrolidin-1-yl)butan-1-one
(+)-2,2-diphenyl-3-methyl-4-morpholinobutyrylpyrrolidine
3-methyl-4-(morpholin-4-yl)-2,2-diphenyl-1-(pyrrolidin-1-yl)butan-1-one
C25H32N2O2
SKF-5137
dextromoramidum
palphium
(+)-3-methyl-4-morpholino-2,2-diphenyl-1-(pyrrolidin-1-yl)butanone
dextromoramide
pyrrolamidolum
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|
| xref |
Reaxys:96553
CiteXplore:2295688
Patent:GB822055
CiteXplore:8931067
KEGG DRUG:D07287
CiteXplore:9584342
ChEMBL:1641545
PubChem Substance:46507896
CiteXplore:89885
Wikipedia:http://en.wikipedia.org/wiki/Dextromoramide
PubChem Compound:9648
CiteXplore:13757828
DrugBank:DB01529
CiteXplore:7632606
ChemSpider:9269
NIST Chemistry WebBook:357-56-2
CASRN:357-56-2
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| CASRN | 357-56-2
|
| prefixIRI | obo2:CHEBI_74274
|
| SMILES |
C[C@H](CN1CCOCC1)C(C(=O)N1CCCC1)(c1ccccc1)c1ccccc1
CC(CN1CCOCC1)C(C(=O)N1CCCC1)(C1=CC=CC=C1)C1=CC=CC=C1
|
| DBname | dextromoramide
|
| InChI | InChI=1S/C25H32N2O2/c1-21(20-26-16-18-29-19-17-26)25(22-10-4-2-5-11-22,23-12-6-3-7-13-23)24(28)27-14-8-9-15-27/h2-7,10-13,21H,8-9,14-20H2,1H3
InChI=1S/C25H32N2O2/c1-21(20-26-16-18-29-19-17-26)25(22-10-4-2-5-11-22,23-12-6-3-7-13-23)24(28)27-14-8-9-15-27/h2-7,10-13,21H,8-9,14-20H2,1H3/t21-/m1/s1
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| subClassOf |
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