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The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Details
Acronym DINTO
Visibility Public
Description DINTO is an OWL ontology that systematically organizes all drug-drug interaction (DDI) related information. Drug-drug interactions (DDIs) form a significant risk group for adverse effects associated with pharmaceutical treatment. These interactions are often reported in the literature, however, they are sparsely represented in machine-readable resources, such as online databases, thesauri or ontologies. DINTO is an ontology that describes and categorizes DDIs and all the possible mechanisms that can lead to them (including both pharmacodynamic and pharmacokinetic DDI mechanisms).
Status Retired
Format OWL
Contact Maria Herrero, maria.herrero@kcl.ac.uk
Categories Health
Submissions
Version Released Uploaded Downloads
1.3 (Parsed, Indexed, Metrics, Annotator) 08/26/2015 02/11/2016 OWL | CSV | RDF/XML | Diff
1.2 (Archived) 08/26/2015 10/14/2015 OWL | Diff
1.2 (Archived) 06/16/2015 06/16/2015 OWL | Diff
1.2 (Archived) 06/16/2015 06/16/2015 OWL | Diff
1 (Archived) 06/24/2014 03/18/2015 OWL
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Metrics
Classes 28,178
Individuals 0
Properties 90
Maximum depth 10
Maximum number of children 11,555
Average number of children 37
Classes with a single child 248
Classes with more than 25 children 30
Classes with no definition 27,971
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Id http://purl.obolibrary.org/obo/CHEBI_74234
http://purl.obolibrary.org/obo/CHEBI_74234
Preferred Name

sepiapterin reductase inhibitor
Synonyms
7,8-dihydrobiopterin:NADP(+) oxidoreductases
7,8-dihydrobiopterin:NADP(+) oxidoreductase
sepiapterin reductase inhibitors
Type http://www.w3.org/2002/07/owl#Class

All Properties

label
sepiapterin reductase inhibitor
prefLabel
sepiapterin reductase inhibitor
Definition
An enzyme inhibitor that interferes with the activity of sepiapterin reductase (EC 1.1.1.153), which plays an important part in the biosynthesis of tetrahydrobiopterin.
prefixIRI
obo2:CHEBI_74234
Synonym
7,8-dihydrobiopterin:NADP(+) oxidoreductases
7,8-dihydrobiopterin:NADP(+) oxidoreductase
sepiapterin reductase inhibitors
subClassOf
type
xref
Wikipedia:Sepiapterin_reductase
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