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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_73044
http://purl.obolibrary.org/obo/CHEBI_73044
|
|---|---|
| Preferred Name | lumiracoxib |
| Synonyms |
2-{2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid
COX 189
lumiracoxibum
{2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid
C15H13ClFNO2
COX-189
COX189
Prexige
2-((2-chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acid
lumiracoxib
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | lumiracoxib
|
|---|---|
| label | lumiracoxib
|
| DBSynonym | cox 189
|
| ATCCode | M01AH06
|
| Definition | An amino acid that is phenylacetic acid which is substituted at position 2 by the nitrogen of 2-chloro-6-fluoroaniline and at position 5 by a methyl group. A highly selective cyclooxygenase 2 inhibitor, it was briefly used for the treatment of osteoarthritis, but was withdrawn due to concersns of hepatotoxicity.
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| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=KHPKQFYUPIUARC-UHFFFAOYSA-N
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| is metabolised by | |
| AHFScode | 28:08.04.08
|
| Synonym |
2-{2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid
COX 189
lumiracoxibum
{2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid
C15H13ClFNO2
COX-189
COX189
Prexige
2-((2-chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acid
lumiracoxib
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|
| xref |
PubChem Compound:151166
ChEMBL:524824
PharmGKB:PA164769031
CASRN:220991-20-8
CiteXplore:15311562
ChemSpider:133236
KEGG DRUG:D03714
PubChem Substance:46506378
CiteXplore:22142375
CiteXplore:22732767
CiteXplore:22621454
CiteXplore:15456339
DrugBank:DB01283
Drugs Product Database (DPD):2288036
CiteXplore:19800190
CiteXplore:22069133
Reaxys:9784107
HMDB:HMDB15403
CiteXplore:17380211
BindingDB:50207446
CiteXplore:21688392
Wikipedia:Lumiracoxib
Wikipedia:http://en.wikipedia.org/wiki/Lumiracoxib
CiteXplore:14965322
PDBeChem:LUR
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| CASRN | 220991-20-8
|
| prefixIRI | obo2:CHEBI_73044
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| SMILES |
CC1=CC(CC(O)=O)=C(NC2=C(F)C=CC=C2Cl)C=C1
Cc1ccc(Nc2c(F)cccc2Cl)c(CC(O)=O)c1
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| DBname | lumiracoxib
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| InChI | InChI=1S/C15H13ClFNO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20)
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| DBBrand |
prexige
prexige (novartis)
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| subClassOf |
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