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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_70735
http://purl.obolibrary.org/obo/CHEBI_70735
|
|---|---|
| Preferred Name | lurasidone |
| Synonyms |
lurasidonum
lurasidona
(1R,2S,6R,7S)-4-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl]methyl}-4-azatricyclo[5.2.1.0?,?]decane-3,5-dione
C28H36N4O2S
lurasidone
(3aR,4S,7R,7aS)-2-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl]methyl}hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | lurasidone
|
|---|---|
| label | lurasidone
|
| DBSynonym | sm-13496
|
| ATCCode | N05AE05
|
| Definition | An N-arylpiperazine that is (3aR,4S,7R,7aS)-2-{[(1R,2R)-2-(piperazin-1-ylmethyl)cyclohexyl]methyl}hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione in which position N4 of the piperazine ring is substituted by a 1,2-benzothiazol-3-yl group. Lurasidone is used (generally as the hydrochloride salt) as an atypical antipsychotic for the treatment of schizophrenia.
Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States. (Wikipedia)
|
| DBSalt | lurasidone hydrochloride
|
| has pharmacological target | |
| type | |
| has role | |
| InChIKey | InChIKey=PQXKDMSYBGKCJA-CVTJIBDQSA-N
|
| is metabolised by | |
| blocks | |
| AHFScode | 28:16.08.04
|
| Synonym | lurasidonum
lurasidona
(1R,2S,6R,7S)-4-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl]methyl}-4-azatricyclo[5.2.1.0?,?]decane-3,5-dione
C28H36N4O2S
lurasidone
(3aR,4S,7R,7aS)-2-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl]methyl}hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
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|
| xref |
CiteXplore:23001538
CASRN:367514-87-2
National Drug Code Directory:63402-312-30
CiteXplore:22217440
CiteXplore:22828971
Patent:EP1652848
Patent:US2012115879
Wikipedia:Lurasidone
CiteXplore:22364325
RxList:http://www.rxlist.com/latuda-drug.htm
CiteXplore:21474903
Wikipedia:http://en.wikipedia.org/wiki/Lurasidone
Patent:US2011263848
CiteXplore:22739469
CiteXplore:21838595
CiteXplore:22570547
CiteXplore:19780705
CiteXplore:22227609
CiteXplore:21349227
CiteXplore:22849428
CiteXplore:22415605
CiteXplore:22900950
ChEMBL:799372
CiteXplore:22395527
CiteXplore:22903391
CiteXplore:22072817
Drugs.com:http://www.drugs.com/cdi/lurasidone.html
CiteXplore:22967786
CiteXplore:22559286
CiteXplore:22929996
CiteXplore:22545643
Patent:EP1637530
Patent:US2011263847
Reaxys:11182976
CiteXplore:22868411
ChEBI:70735
CiteXplore:22675261
CiteXplore:22776634
CiteXplore:22332980
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| CASRN | 367514-87-2
|
| prefixIRI | obo2:CHEBI_70735
|
| related with | |
| SMILES |
O=C1[C@H]2[C@@H]3CC[C@@H](C3)[C@H]2C(=O)N1C[C@@H]1CCCC[C@H]1CN1CCN(CC1)C1=NSC2=CC=CC=C12
[H][C@@]12[C@H]3CC[C@H](C3)[C@]1([H])C(=O)N(C[C@@H]1CCCC[C@H]1CN1CCN(CC1)c1nsc3ccccc13)C2=O
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| may interact with |
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| InChI | InChI=1S/C28H36N4O2S/c33-27-24-18-9-10-19(15-18)25(24)28(34)32(27)17-21-6-2-1-5-20(21)16-30-11-13-31(14-12-30)26-22-7-3-4-8-23(22)35-29-26/h3-4,7-8,18-21,24-25H,1-2,5-6,9-17H2/t18-,19+,20-,21-,24+,25-/m0/s1
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| DBBrand | latuda
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| subClassOf |
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