The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	mirtazapine
Synonyms	5-methyl-2,5,19-triazatetracyclo[13.4.0.0^{2,7}.0^{8,13}]nonadeca-1(19),8(13),9,11,15,17-hexaene Mirtazapine mirtazapina mirtazapinum 2-methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine mirtazapine C17H19N3
ID	http://purl.obolibrary.org/obo/CHEBI_6950
activates	http://purl.obolibrary.org/obo/dinto_3960
AHFScode	28:16.04.92
ATCCode	N06AX11
binds	http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_0392 http://purl.obolibrary.org/obo/dinto_1123 http://purl.obolibrary.org/obo/dinto_1135 http://purl.obolibrary.org/obo/dinto_0510 http://purl.obolibrary.org/obo/dinto_1071 http://purl.obolibrary.org/obo/dinto_3960 http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_1221
blocks	http://purl.obolibrary.org/obo/dinto_0510 http://purl.obolibrary.org/obo/dinto_1071 http://purl.obolibrary.org/obo/dinto_0392 http://purl.obolibrary.org/obo/dinto_1123 http://purl.obolibrary.org/obo/dinto_1135
CASRN	61337-67-5
DBBrand	norset mirtabene mirtazon avanza zispin remeron soltab remergon rexer mirtaz promyrtil remergil axit remeron
DBname	mirtazapine
DBSynonym	mirtazapine [usan:ban:inn] mirtazepine mirtazapinum [inn-latin] mepirzepine mirtazapina [inn-spanish]
Definition	A tetracyclic antidepressant that has formula C17H19N3.
has effect	http://purl.obolibrary.org/obo/OAE_0000496 http://purl.obolibrary.org/obo/OAE_0000447 http://purl.obolibrary.org/obo/OAE_0000424 http://purl.obolibrary.org/obo/OAE_0000395 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0001120 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000573 http://purl.obolibrary.org/obo/OAE_0000604 http://purl.obolibrary.org/obo/OAE_0000888 http://purl.obolibrary.org/obo/OAE_0001098 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000479 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0000198 http://purl.obolibrary.org/obo/OAE_0000596 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0000825 http://purl.obolibrary.org/obo/OAE_0000411 http://purl.obolibrary.org/obo/OAE_0001186 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0001489 http://purl.obolibrary.org/obo/OAE_0000611 http://purl.obolibrary.org/obo/OAE_0000567 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000545 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0000412 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000317 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000482 http://purl.obolibrary.org/obo/OAE_0001280 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000250 http://purl.obolibrary.org/obo/OAE_0001073 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000539 http://purl.obolibrary.org/obo/OAE_0000612 http://purl.obolibrary.org/obo/OAE_0000340 http://purl.obolibrary.org/obo/OAE_0001063 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0001340 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000691 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0000517 http://purl.obolibrary.org/obo/OAE_0000802 http://purl.obolibrary.org/obo/OAE_0001024 http://purl.obolibrary.org/obo/OAE_0000498 http://purl.obolibrary.org/obo/OAE_0000502 http://purl.obolibrary.org/obo/OAE_0000995 http://purl.obolibrary.org/obo/OAE_0001050 http://purl.obolibrary.org/obo/OAE_0001243 http://purl.obolibrary.org/obo/OAE_0001295 http://purl.obolibrary.org/obo/OAE_0001515 http://purl.obolibrary.org/obo/OAE_0000526 http://purl.obolibrary.org/obo/OAE_0001308 http://purl.obolibrary.org/obo/OAE_0001070 http://purl.obolibrary.org/obo/OAE_0001529 http://purl.obolibrary.org/obo/OAE_0000309 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000842 http://purl.obolibrary.org/obo/OAE_0000184 http://purl.obolibrary.org/obo/OAE_0000533 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000613 http://purl.obolibrary.org/obo/OAE_0000894 http://purl.obolibrary.org/obo/OAE_0000473 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000752 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000038 http://purl.obolibrary.org/obo/OAE_0000968 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0002122 http://purl.obolibrary.org/obo/OAE_0001742 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000405 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000898 http://purl.obolibrary.org/obo/OAE_0000647 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0000194 http://purl.obolibrary.org/obo/OAE_0001152 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000491 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000421 http://purl.obolibrary.org/obo/OAE_0001147 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0001052 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000275 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000470 http://purl.obolibrary.org/obo/OAE_0001291 http://purl.obolibrary.org/obo/OAE_0000501 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0000462 http://purl.obolibrary.org/obo/OAE_0001309 http://purl.obolibrary.org/obo/OAE_0000716 http://purl.obolibrary.org/obo/OAE_0001170 http://purl.obolibrary.org/obo/OAE_0000766 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000049 http://purl.obolibrary.org/obo/OAE_0000350 http://purl.obolibrary.org/obo/OAE_0000304
has pharmacological target	http://purl.obolibrary.org/obo/dinto_0392 http://purl.obolibrary.org/obo/dinto_1123 http://purl.obolibrary.org/obo/dinto_1135
has role	http://purl.obolibrary.org/obo/CHEBI_37955 http://purl.obolibrary.org/obo/CHEBI_37956 http://purl.obolibrary.org/obo/CHEBI_35474 http://purl.obolibrary.org/obo/CHEBI_48279 http://purl.obolibrary.org/obo/CHEBI_37890
InChI	InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3
InChIKey	InChIKey=RONZAEMNMFQXRA-UHFFFAOYSA-N
induces	http://purl.obolibrary.org/obo/dinto_2993
inhibits	http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0901
is metabolised by	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1221
is substrate of	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1221
label	mirtazapine
may interact with	http://purl.obolibrary.org/obo/CHEBI_32250 http://purl.obolibrary.org/obo/CHEBI_9943 http://purl.obolibrary.org/obo/CHEBI_8107 http://purl.obolibrary.org/obo/CHEBI_4888 http://purl.obolibrary.org/obo/CHEBI_42944 http://purl.obolibrary.org/obo/dinto_DB00857 http://purl.obolibrary.org/obo/CHEBI_8874 http://purl.obolibrary.org/obo/dinto_DB00726 http://purl.obolibrary.org/obo/dinto_DB00532 http://purl.obolibrary.org/obo/CHEBI_53289 http://purl.obolibrary.org/obo/dinto_DB00780 http://purl.obolibrary.org/obo/CHEBI_9654 http://purl.obolibrary.org/obo/dinto_DB00582 http://purl.obolibrary.org/obo/dinto_DB00427 http://purl.obolibrary.org/obo/CHEBI_5138 http://purl.obolibrary.org/obo/dinto_DB01247 http://purl.obolibrary.org/obo/dinto_DB00752 http://purl.obolibrary.org/obo/CHEBI_63620 http://purl.obolibrary.org/obo/CHEBI_10124 http://purl.obolibrary.org/obo/dinto_DB01320 http://purl.obolibrary.org/obo/CHEBI_46631 http://purl.obolibrary.org/obo/dinto_DB00976 http://purl.obolibrary.org/obo/dinto_DB06700
modulates	http://purl.obolibrary.org/obo/dinto_0510 http://purl.obolibrary.org/obo/dinto_1071 http://purl.obolibrary.org/obo/dinto_0392 http://purl.obolibrary.org/obo/dinto_1123 http://purl.obolibrary.org/obo/dinto_1135 http://purl.obolibrary.org/obo/dinto_3960
prefixIRI	obo2:CHEBI_6950
prefLabel	mirtazapine
SMILES	CN1CCN2C(C1)C1=CC=CC=C1CC1=C2N=CC=C1 CN1CCN2C(C1)c1ccccc1Cc1cccnc21
Synonym	5-methyl-2,5,19-triazatetracyclo[13.4.0.0^{2,7}.0^{8,13}]nonadeca-1(19),8(13),9,11,15,17-hexaene Mirtazapine mirtazapina mirtazapinum 2-methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine mirtazapine C17H19N3
xref	CASRN:61337-67-5 ChEBI:6950 ChemSpider:4060 Patent:DE2614406 Beilstein:549345 DrugBank:DB00370 KEGG DRUG:D00563 Patent:US4062848 ChEMBL:127610 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/rem1371.shtml RxList:http://www.rxlist.com/cgi/generic/mirtaz.htm PharmGKB:PA450522 Wikipedia:Mirtazapine Drugs.com:http://www.drugs.com/cdi/mirtazapine.html PubChem Substance:46506965 KEGG COMPOUND:C07570 National Drug Code Directory:0185-0020-30 Wikipedia:http://en.wikipedia.org/wiki/Mirtazapine PubChem Compound:4205 Drugs Product Database (DPD):2256126
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_6950	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6950	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6950	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6950	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6950	DDSS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6950	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6950	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6950	NIFSTD	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6950	DRON	SAME_URI
https://bioportal.bioontology.org/ontologies/STMSO#Mirtazapine	STMSO	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148449	NDFRT	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0049506	OCHV	LOOM
http://www.drugbank.ca/drugs/DB00370	FTC	LOOM
http://purl.bioontology.org/ontology/MESH/D000078785	MESH	LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass374ae25c_1fe3_4c1a_bf63_12a518dd4f8d	WWECA	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000559298	PDQ	LOOM
http://purl.bioontology.org/ontology/RCD/daB..	RCD	LOOM
http://www.case.edu/EpilepsyOntology.owl#Mirtazapine	EPSO	LOOM
http://purl.jp/bio/4/id/200906032503840605	IOBC	LOOM
http://purl.bioontology.org/ontology/LNC/LP19150-9	LOINC	LOOM
http://www.case.edu/EpSO.owl#Mirtazapine	MEPO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026446	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/ATC/N06AX11	ATC	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU007402	LOINC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C035133	RH-MESH	LOOM
http://www.co-ode.org/ontologies/galen#Mirtazapine	GALEN	LOOM
http://doe-generated-ontology.com/OntoAD#C0049506	ONTOAD	LOOM
http://purl.bioontology.org/ontology/RXNORM/15996	RXNORM	LOOM
http://purl.obolibrary.org/obo/CHEBI_6950	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_6950	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_6950	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_6950	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_6950	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_6950	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_6950	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_6950	NIFSTD	LOOM
http://purl.obolibrary.org/obo/CHEBI_6950	DRON	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#13392	OCHV	LOOM
http://purl.bioontology.org/ontology/NDDF/006054	NDDF	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29265	NCIT	LOOM
http://stirdf.jst.go.jp/id/200907007216164428	IOBC	LOOM
http://purl.obolibrary.org/obo/NCIT_C29265	BERO	LOOM
https://go.drugbank.com/drugs/DB00370	MDM	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/386847004	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/VANDF/4020978	VANDF	LOOM