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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_6933
http://purl.obolibrary.org/obo/CHEBI_6933
|
|---|---|
| Preferred Name | midodrine |
| Synonyms |
C12H18N2O4
DL-N1-(beta-Hydroxy-2,5-dimethoxyphenethyl)glycinamid
(+-)-2-amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide
2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide
2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamide
midodrine
midodrina
midodrinum
rac-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]glycinamide
1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | midodrine
|
|---|---|
| label | midodrine
|
| DBSynonym |
midodrina [inn-spanish]
midodrine hcl
midodrin
midodrine hydrochloride
midodrinum [inn-latin]
|
| ATCCode | C01CA17
|
| Definition | An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.
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| has effect |
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| has pharmacological target | |
| activates | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=PTKSEFOSCHHMPD-UHFFFAOYSA-N
|
| AHFScode |
12:12.00
12:12.04
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| Synonym |
C12H18N2O4
DL-N1-(beta-Hydroxy-2,5-dimethoxyphenethyl)glycinamid
(+-)-2-amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide
2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide
2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamide
midodrine
midodrina
midodrinum
rac-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]glycinamide
1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol
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| xref |
PubChem Substance:46507373
CiteXplore:23051063
CiteXplore:19522958
Wikipedia:http://en.wikipedia.org/wiki/Midodrine
ChEMBL:775163
CASRN:42794-76-3
Patent:US3340298
DrugBank:DB00211
CiteXplore:21343575
PubChem Compound:4195
KEGG COMPOUND:C07890
ChemSpider:4050
CiteXplore:21801220
ChEBI:6933
Patent:GB1003659
Drugs Product Database (DPD):1934406
CiteXplore:18410283
CiteXplore:18840368
CiteXplore:22436941
RxList:http://www.rxlist.com/cgi/generic3/midodrine.htm
Wikipedia:Midodrine
PharmGKB:PA164749381
HMDB:HMDB14356
CiteXplore:17901021
CiteXplore:20844343
Drugs.com:http://www.drugs.com/cdi/midodrine.html
CiteXplore:20376815
KEGG DRUG:D08220
National Drug Code Directory:0245-0211-11
CiteXplore:15273244
CiteXplore:11096750
Beilstein:2384653
CiteXplore:16676655
Reaxys:2384653
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| CASRN | 133163-28-7
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| prefixIRI | obo2:CHEBI_6933
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| related with | |
| SMILES |
COC1=CC(C(O)CNC(=O)CN)=C(OC)C=C1
COc1ccc(OC)c(c1)C(O)CNC(=O)CN
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| may interact with |
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| DBname | midodrine
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| InChI | InChI=1S/C12H18N2O4/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16)
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| DBBrand | proamatine
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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