The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_6912 http://purl.obolibrary.org/obo/CHEBI_6912
Preferred Name	alpha-methyl-L-tyrosine
Synonyms	metirosina alpha-methyl-L-tyrosine L-alpha-Methyltyrosine alpha-methyl-p-tyrosine Metyrosine (-)-alpha-Methyl-L-tyrosine (2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid metirosine Methyltyrosine alpha-methyl-L-p-tyrosine C10H13NO3 metirosinum (S)-alpha-Methyltyrosine alpha-Methyltyrosine alpha-methyl-para-tyrosine See more See less
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	alpha-methyl-L-tyrosine
label	alpha-methyl-L-tyrosine
DBSynonym	metirosine methyltyrosine
ATCCode	C02KB01
Definition	An L-tyrosine derivative that consists of L-tyrosine bering an additional methyl substituent at position 2. An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma.
has effect	http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000335 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000881 http://purl.obolibrary.org/obo/OAE_0000402 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_3925
type	http://www.w3.org/2002/07/owl#Class
binds	http://purl.obolibrary.org/obo/dinto_3925
has role	http://purl.obolibrary.org/obo/CHEBI_63932 http://purl.obolibrary.org/obo/CHEBI_35674
InChIKey	InChIKey=NHTGHBARYWONDQ-JTQLQIEISA-N
Synonym	metirosina alpha-methyl-L-tyrosine L-alpha-Methyltyrosine alpha-methyl-p-tyrosine Metyrosine (-)-alpha-Methyl-L-tyrosine (2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid metirosine Methyltyrosine alpha-methyl-L-p-tyrosine C10H13NO3 metirosinum (S)-alpha-Methyltyrosine alpha-Methyltyrosine alpha-methyl-para-tyrosine See more See less
xref	CASRN:672-87-7 National Drug Code Directory:0006-0690-68 ChemSpider:390103 Drugs.com:http://www.drugs.com/cdi/metyrosine.html ChEMBL:774813 Reaxys:2368400 DrugBank:DB00765 PubChem Substance:46506079 Wikipedia:Metirosine KEGG DRUG:D00762 PubChem Compound:441350 KEGG COMPOUND:C07921 PharmGKB:PA450487 RxList:http://www.rxlist.com/cgi/generic2/metyrosine.htm See more See less
CASRN	672-87-7
prefixIRI	obo2:CHEBI_6912
SMILES	C[C@](N)(CC1=CC=C(O)C=C1)C(O)=O C[C@](N)(Cc1ccc(O)cc1)C(O)=O
DBname	metyrosine
InChI	InChI=1S/C10H13NO3/c1-10(11,9(13)14)6-7-2-4-8(12)5-3-7/h2-5,12H,6,11H2,1H3,(H,13,14)/t10-/m0/s1
DBBrand	demser
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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