Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_68579
http://purl.obolibrary.org/obo/CHEBI_68579
|
|---|---|
| Preferred Name | rivaroxaban |
| Synonyms |
Xarelto
C19H18ClN3O5S
5-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl}thiophene-2-carboxamide
5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide
rivaroxaban
BAY 59-7939
BAY59-7939
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | rivaroxaban
|
|---|---|
| label | rivaroxaban
|
| DBSynonym | bay 59-7939
|
| ATCCode | B01AF01
|
| Definition | A carboxamide obtained by formal condensation of the carboxy group of 5-chlorothiophene-2-carboxylic acid with the amino group of 4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one. An anticoagulant used for prophylaxis of venous thromboembolism in patients with knee or hip replacement surgery.
|
| has effect |
See more
See less
|
| has pharmacological target | |
| type | |
| has role | |
| InChIKey | InChIKey=KGFYHTZWPPHNLQ-AWEZNQCLSA-N
|
| is metabolised by | |
| blocks | |
| AHFScode | 20.12.04.14
|
| Synonym | Xarelto
C19H18ClN3O5S
5-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl}thiophene-2-carboxamide
5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide
rivaroxaban
BAY 59-7939
BAY59-7939
See more
See less
|
| xref |
National Drug Code Directory:50458-579-10
CiteXplore:22042412
CiteXplore:22884545
CiteXplore:22958812
CiteXplore:22187012
CiteXplore:22542983
CiteXplore:22871192
CiteXplore:22422332
Wikipedia:Rivaroxaban
Patent:US2011034453
CiteXplore:22534269
CiteXplore:22387577
ChEBI:68579
Wikipedia:http://en.wikipedia.org/wiki/Rivaroxaban
CASRN:366789-02-8
Patent:US2011288294
CiteXplore:22173426
CiteXplore:22651881
CiteXplore:22777255
CiteXplore:22242932
Reaxys:10206739
Patent:WO2004060887
Patent:EP1685841
CiteXplore:22533680
CiteXplore:22701330
CiteXplore:23014816
CiteXplore:22800431
CiteXplore:23006523
CiteXplore:22740145
CiteXplore:22272729
Patent:US2005182055
Patent:US2009036504
Patent:US2010151011
Patent:WO2008140220
Patent:WO2012035057
CiteXplore:22811404
Patent:WO2005068456
CiteXplore:22932305
Patent:US2007026065
Patent:US2011152266
CiteXplore:22372178
Patent:WO2011080341
PDBeChem:RIV
Drugs.com:http://www.drugs.com/cdi/rivaroxaban.html
CiteXplore:22534775
ChEMBL:428601
CiteXplore:22664783
Patent:US2011112083
DrugBank:DB06228
RxList:http://www.rxlist.com/xarelto-drug.htm
Patent:WO2012051692
KEGG DRUG:D07086
Patent:US7816355
See more
See less
|
| CASRN | 366789-02-8
|
| prefixIRI | obo2:CHEBI_68579
|
| is transported by | |
| SMILES |
[H][C@]1(CNC(=O)c2ccc(Cl)s2)CN(C(=O)O1)c1ccc(cc1)N1CCOCC1=O
ClC1=CC=C(S1)C(=O)NC[C@H]1CN(C(=O)O1)C1=CC=C(C=C1)N1CCOCC1=O
|
| may interact with |
See more
See less
|
| DBname | rivaroxaban
|
| InChI | InChI=1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m0/s1
|
| DBBrand | xarelto
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |