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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_68554
http://purl.obolibrary.org/obo/CHEBI_68554
|
|---|---|
| Preferred Name | deferiprone |
| Synonyms |
1,2-Dimethyl-3-hydroxypyrid-4-one
3-Hydroxy-1,2-dimethyl-4(1H)-pyridone
3-hydroxy-1,2-dimethylpyridin-4(1H)-one
Ferriprox
3-hydroxy-1,2-dimethyl-1,4-dihydropyridin-4-one
C7H9NO2
deferiprone
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | deferiprone
|
|---|---|
| label | deferiprone
|
| DBSynonym |
dimethylhydroxypyridone
deferiproni
pl-1
deferipron
cp-20
dn-180-01-af
deferiprona
deferipronum
deferypron
apo-066
d?f?riprone
l-1
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|
| ATCCode | V03AC02
|
| Definition | Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired. FDA approved on October 14, 2011.
A pyridone that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.
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| has effect |
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| type | |
| has role | |
| InChIKey | InChIKey=TZXKOCQBRNJULO-UHFFFAOYSA-N
|
| is metabolised by | |
| AHFScode | 64:00
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| Synonym |
1,2-Dimethyl-3-hydroxypyrid-4-one
3-Hydroxy-1,2-dimethyl-4(1H)-pyridone
3-hydroxy-1,2-dimethylpyridin-4(1H)-one
Ferriprox
3-hydroxy-1,2-dimethyl-1,4-dihydropyridin-4-one
C7H9NO2
deferiprone
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|
| xref |
CiteXplore:22468647
CiteXplore:22621771
ChEMBL:212090
CiteXplore:22130677
ChEBI:68554
CiteXplore:22622672
Drugs.com:http://www.drugs.com/mtm/deferiprone.html
CiteXplore:22943064
CiteXplore:22180427
Wikipedia:http://en.wikipedia.org/wiki/Deferiprone
CiteXplore:22565013
CiteXplore:22034002
CiteXplore:22572843
CiteXplore:22459459
CiteXplore:22025507
CASRN:30652-11-0
CiteXplore:22978744
CiteXplore:22171759
CiteXplore:21853518
National Drug Code Directory:52609-0006-1
Reaxys:1447108
Wikipedia:Deferiprone
CiteXplore:22406440
CiteXplore:22579919
RxList:http://www.rxlist.com/ferriprox-drug.htm
CiteXplore:22457166
KEGG DRUG:D07416
CiteXplore:22664119
CASRN:1447108
CiteXplore:22354281
CiteXplore:22850524
CiteXplore:22759897
CiteXplore:22277065
CiteXplore:22454828
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| CASRN | 30652-11-0
|
| prefixIRI | obo2:CHEBI_68554
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| SMILES |
Cc1c(O)c(=O)ccn1C
CN1C=CC(=O)C(O)=C1C
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| may interact with |
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| InChI | InChI=1S/C7H9NO2/c1-5-7(10)6(9)3-4-8(5)2/h3-4,10H,1-2H3
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| DBBrand | ferriprox
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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