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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_681848
http://purl.obolibrary.org/obo/CHEBI_681848
|
|---|---|
| Preferred Name | doxapram |
| Synonyms |
(+-)-doxapram
1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone
C24H30N2O2
Doxapram
1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one
doxapram
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | doxapram
|
|---|---|
| label | doxapram
|
| ATCCode | R07AB01
|
| Definition | A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
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| has effect |
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| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=XFDJYSQDBULQSI-UHFFFAOYSA-N
|
| Synonym |
(+-)-doxapram
1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone
C24H30N2O2
Doxapram
1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one
doxapram
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|
| xref |
National Drug Code Directory:55390-035-01
Patent:BE613734
DrugBank:DB00561
CiteXplore:4122029
CiteXplore:19663568
Beilstein:628691
Patent:US3192206
Wikipedia:http://en.wikipedia.org/wiki/Doxapram
ChemSpider:3044
Wikipedia:Doxapram
PubChem Compound:3156
CiteXplore:527638
Drugs Product Database (DPD):1914154
Drugs.com:http://www.drugs.com/cdi/doxapram.html
KEGG DRUG:D07873
PubChem Substance:46506829
CiteXplore:20140700
RxList:http://www.rxlist.com/cgi/generic2/doxapram.htm
ChEBI:681848
Reaxys:628691
PharmGKB:PA164784026
CASRN:309-29-5
CiteXplore:4126096
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| CASRN | 309-29-5
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| prefixIRI | obo2:CHEBI_681848
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| SMILES |
CCN1CC(CCN2CCOCC2)C(C1=O)(c1ccccc1)c1ccccc1
CCN1CC(CCN2CCOCC2)C(C1=O)(C1=CC=CC=C1)C1=CC=CC=C1
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| DBname | doxapram
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| InChI | InChI=1S/C24H30N2O2/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21/h3-12,22H,2,13-19H2,1H3
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| DBBrand |
stimulexin
doxapram hydrochloride
doxapram hcl
dopram
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| subClassOf |
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