The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Id http://purl.obolibrary.org/obo/CHEBI_65353
http://purl.obolibrary.org/obo/CHEBI_65353
Preferred Name

lorcaserin
Synonyms
C11H14ClN
(1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
lorcaserin
Type http://www.w3.org/2002/07/owl#Class

All Properties

prefLabel
lorcaserin
label
lorcaserin
DBSynonym
apd356
apd-356
Definition
Lorcaserin (previously APD-356), a highly selective 5HT2C receptor agonist, is used for the treatment of obesity. It has been shown to reduce body weight and food intake in animal models of obesity, and it is thought that targeting the 5HT2C receptor may alter body weight by regulating satiety. Lorcaserin is marketed as a salt form called Belviq, which is lorcaserin hydrochloride.
A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine substituted at position 1 by a methyl group and a t position 6 by a chloro group.
DBSalt
lorcaserin hydrochloride
type
has role
InChIKey
InChIKey=XTTZERNUQAFMOF-QMMMGPOBSA-N
is metabolised by
Synonym
C11H14ClN
(1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
lorcaserin
xref
ChEBI:65350
ChEMBL:401194
Wikipedia:http://en.wikipedia.org/wiki/Lorcaserin
Reaxys:9904422
Drugs.com:http://www.drugs.com/mtm/lorcaserin.html
CASRN:616202-92-7
RxList:http://www.rxlist.com/belviq-drug.htm
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CASRN
846589-98-8
prefixIRI
obo2:CHEBI_65353
related with
SMILES
C[C@H]1CNCCc2ccc(Cl)cc12
may interact with
InChI
InChI=1S/C11H14ClN/c1-8-7-13-5-4-9-2-3-10(12)6-11(8)9/h2-3,6,8,13H,4-5,7H2,1H3/t8-/m0/s1
DBBrand
belviq
subClassOf
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