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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_65349
http://purl.obolibrary.org/obo/CHEBI_65349
|
|---|---|
| Preferred Name | mirabegron |
| Synonyms |
Myrbetriq
C21H24N4O2S
2-(2-amino-1,3-thiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)phenyl]acetamide
mirabegron
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | mirabegron
|
|---|---|
| label | mirabegron
|
| DBSynonym | ym-178
|
| ATCCode | G04BD12
|
| Definition | Mirabegron is a beta-3 adrenergic receptor agonist for the management of overactive bladder. It is an alternative to antimuscarinic drugs for this indication. FDA approved on June 28, 2012.
A carboxamide obtained by formal condensation of the carboxy group of 2-amino-1,3-thiazol-4-ylacetic acid with the anilino group of (1R)-2-{[2-(4-aminophenyl)ethyl]amino}-1-phenylethanol. Used for the treatment of overactive bladder syndrome.
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| has pharmacological target | |
| activates | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=PBAPPPCECJKMCM-IBGZPJMESA-N
|
| is metabolised by | |
| AHFScode | 86:12
|
| Synonym |
Myrbetriq
C21H24N4O2S
2-(2-amino-1,3-thiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)phenyl]acetamide
mirabegron
|
| xref |
CiteXplore:22411211
KEGG DRUG:D09535
CiteXplore:20878594
CiteXplore:22734513
National Drug Code Directory:0469-2602-30
CiteXplore:22269146
ChEMBL:1469608
CiteXplore:22317789
Wikipedia:http://en.wikipedia.org/wiki/Mirabegron
CiteXplore:21142693
Patent:EP1559427
Drugs.com:http://www.drugs.com/cdi/mirabegron.html
Patent:EP2119700
Reaxys:11023250
CiteXplore:22430195
CiteXplore:22734512
CiteXplore:22687876
CiteXplore:22509825
CiteXplore:21510978
ChEBI:65349
RxList:http://www.rxlist.com/myrbetriq-drug.htm
CiteXplore:22821779
CASRN:223673-61-8
CiteXplore:22691895
CiteXplore:22384458
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| CASRN | 223673-61-8
|
| prefixIRI | obo2:CHEBI_65349
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| is transported by | |
| is substrate of | |
| SMILES |
Nc1nc(CC(=O)Nc2ccc(CCNC[C@H](O)c3ccccc3)cc2)cs1
NC1=NC(CC(=O)NC2=CC=C(CCNC[C@H](O)C3=CC=CC=C3)C=C2)=CS1
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| may interact with |
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| InChI | InChI=1S/C21H24N4O2S/c22-21-25-18(14-28-21)12-20(27)24-17-8-6-15(7-9-17)10-11-23-13-19(26)16-4-2-1-3-5-16/h1-9,14,19,23,26H,10-13H2,(H2,22,25)(H,24,27)/t19-/m0/s1
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| DBBrand |
myrbetriq
metmiga
betanis
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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