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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_65173
http://purl.obolibrary.org/obo/CHEBI_65173
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|---|---|
| Preferred Name | iloperidone |
| Synonyms |
Fanapta
Fanapt
1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1- piperidinyl]propoxy]-3-methoxyphenyl]ethanone
1-(4-{3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy}-3-methoxyphenyl)ethanone
iloperidonum
C24H27FN2O4
iloperidone
Zomaril
4'-(3-(4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidino)propoxy)-3'-methoxyacetophenone
1-(4-{3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy}-3-methoxyphenyl)ethan-1-one
iloperidona
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | iloperidone
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|---|---|
| label | iloperidone
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| DBSynonym | hp 873
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| ATCCode | N05AX14
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| Definition | Iloperidone is an atypical antipsychotic for the treatment of schizophrenia symptoms. Hoechst Marion Roussel Inc. made initial inquiries into the drug; however, in May 1996, they discontinued research, and in June 1997 gave research rights to Titan Pharmaceuticals. Titan then handed over worldwide development, manufacturing and marketing rights to Novartis in August 1998. On June 9, 2004, Titan Pharmaceuticals announced that the Phase III development rights have been acquired by Vanda Pharmaceuticals. FDA approved on May 9, 2009.
A member of the class of piperidines that is the 4-acetyl-2-methoxyphenyl ether of 3-(piperidin-1-yl)propan-1-ol which is substituted at position 4 of the piperidine ring by a 6-fluoro-1,2-benzoxazol-3-yl group. A member of the group of second generation antipsychotics (also known as an atypical antipsychotics), it is used for the treatment of schizophrenia.
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| has pharmacological target | |
| type | |
| has role | |
| InChIKey | InChIKey=XMXHEBAFVSFQEX-UHFFFAOYSA-N
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| is metabolised by | |
| blocks |
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| AHFScode | 28:16.08.04
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| Synonym |
Fanapta
Fanapt
1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1- piperidinyl]propoxy]-3-methoxyphenyl]ethanone
1-(4-{3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy}-3-methoxyphenyl)ethanone
iloperidonum
C24H27FN2O4
iloperidone
Zomaril
4'-(3-(4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidino)propoxy)-3'-methoxyacetophenone
1-(4-{3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy}-3-methoxyphenyl)ethan-1-one
iloperidona
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| xref |
CiteXplore:21600386
ChemSpider:64459
CiteXplore:22453868
CiteXplore:21289324
Drugs.com:http://www.drugs.com/fanapt.html
Wikipedia:Iloperidone
Wikipedia:http://en.wikipedia.org/wiki/Iloperidone
CiteXplore:21474903
BindingDB:50034043
National Drug Code Directory:43068-110-02
CiteXplore:22617084
RxList:http://www.rxlist.com/fanapt-drug.htm
CiteXplore:22161738
CiteXplore:22217439
Reaxys:7233425
CASRN:133454-47-4
SUBMITTER:133454-47-4
PubChem Compound:71360
PharmGKB:PA161199368
SUBMITTER:D02666
CiteXplore:22465688
ChEMBL:113949
PubChem Substance:12014542
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| CASRN | 133454-47-4
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| prefixIRI | obo2:CHEBI_65173
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| SMILES |
COC1=C(OCCCN2CCC(CC2)C2=NOC3=C2C=CC(F)=C3)C=CC(=C1)C(C)=O
COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O
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| may interact with |
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| InChI | InChI=1S/C24H27FN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3
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| DBBrand |
fiapta
fanapt
zomaril
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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