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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_64354
http://purl.obolibrary.org/obo/CHEBI_64354
|
|---|---|
| Preferred Name | metolazone |
| Synonyms |
7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide
Zaroxolyn
C16H16ClN3O3S
7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide
7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
metolazona
metolazone
2-Methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone
metolazonum
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | metolazone
|
|---|---|
| label | metolazone
|
| DBSynonym |
metolazona [inn-spanish]
metolazonum [inn-latin]
|
| ATCCode | C03BA08
|
| Definition | A quinazoline that consists of 1,2,3,4-tetrahydroquinazolin-4-one bearing additional methyl, 2-tolyl, sulfamyl and chloro substituents at positions 2, 3, 6 and 7 respectively. A quinazoline diuretic, with properties similar to thiazide diuretics.
|
| altId | CHEBI:6903
|
| has effect |
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| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=AQCHWTWZEMGIFD-UHFFFAOYSA-N
|
| AHFScode | 40:28.24
|
| Synonym |
7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide
Zaroxolyn
C16H16ClN3O3S
7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide
7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
metolazona
metolazone
2-Methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone
metolazonum
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|
| xref |
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/zar1495.shtml
PubChem Compound:4170
CiteXplore:12671341
Drugs.com:http://www.drugs.com/cdi/metolazone.html
NIST Chemistry WebBook:17560-51-9
CiteXplore:21886902
Patent:US2008139593
CiteXplore:1886511
DrugBank:DB00524
CASRN:17560-51-9
CiteXplore:15095363
National Drug Code Directory:0378-6172-01
CiteXplore:9089428
PubChem Substance:46509058
Drugs Product Database (DPD):888400
Reaxys:965506
CiteXplore:16717105
CiteXplore:1946137
CiteXplore:16908225
CiteXplore:16538931
CiteXplore:16189620
Wikipedia:Metolazone
ChemSpider:4026
KEGG DRUG:D00431
CiteXplore:1593359
Wikipedia:http://en.wikipedia.org/wiki/Metolazone
ChEMBL:173548
CiteXplore:8205244
BindingDB:25899
CiteXplore:2071258
Patent:US3360518
RxList:http://www.rxlist.com/cgi/generic2/metolazone.htm
PharmGKB:PA164781022
CiteXplore:8870895
CiteXplore:21387350
CiteXplore:8199745
CiteXplore:1928234
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|
| CASRN | 17560-51-9
|
| prefixIRI | obo2:CHEBI_64354
|
| SMILES |
CC1NC2=CC(Cl)=C(C=C2C(=O)N1C1=CC=CC=C1C)S(N)(=O)=O
CC1Nc2cc(Cl)c(cc2C(=O)N1c1ccccc1C)S(N)(=O)=O
|
| DBname | metolazone
|
| InChI | InChI=1S/C16H16ClN3O3S/c1-9-5-3-4-6-14(9)20-10(2)19-13-8-12(17)15(24(18,22)23)7-11(13)16(20)21/h3-8,10,19H,1-2H3,(H2,18,22,23)
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| DBBrand |
microx
zaroxolyn
metalozone
metenix
xuret
oldren
metalazone
diulo
mykrox
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| subClassOf |
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