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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_64323
http://purl.obolibrary.org/obo/CHEBI_64323
|
|---|---|
| Preferred Name | memantine hydrochloride |
| Synonyms |
3,5-dimethyltricyclo(3.3.1.1(3,7))decan-1-amine hydrochloride
Memantine HCl
memantine.HCl
3,5-dimethyladamantan-1-aminium chloride
3,5-dimethyladamantan-1-amine
1-Amino-3,5-dimethyladamantane hydrochloride
3,5-Dimethyl-1-adamantanamine hydrochloride
C12H22ClN
Namenda
C12H21N
3,5-dimethyladamantan-1-amine hydrochloride
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | memantine hydrochloride
|
|---|---|
| label | memantine hydrochloride
|
| DBSynonym |
memantine [inn]
memantine hcl
memantinum [inn-latin]
memantina [inn-spanish]
memantine hydrochloride
|
| ATCCode | N06DX01
|
| Definition | A hydrochloride obtained by reaction of memantine with one equivalent of hydrochloric acid. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.
|
| has effect |
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|
| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey |
InChIKey=LDDHMLJTFXJGPI-UHFFFAOYSA-N
InChIKey=BUGYDGFZZOZRHP-UHFFFAOYSA-N
|
| blocks | |
| AHFScode | 28:92.00
|
| Synonym |
3,5-dimethyltricyclo(3.3.1.1(3,7))decan-1-amine hydrochloride
Memantine HCl
memantine.HCl
3,5-dimethyladamantan-1-aminium chloride
3,5-dimethyladamantan-1-amine
1-Amino-3,5-dimethyladamantane hydrochloride
3,5-Dimethyl-1-adamantanamine hydrochloride
C12H22ClN
Namenda
C12H21N
3,5-dimethyladamantan-1-amine hydrochloride
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|
| xref |
CiteXplore:21792308
CiteXplore:20926740
CiteXplore:21220675
RxList:http://www.rxlist.com/cgi/generic3/namenda.htm
Wikipedia:http://en.wikipedia.org/wiki/Memantine
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/cx1682.shtml
ChemSpider:3914
CiteXplore:21268245
KEGG DRUG:D04905
Patent:US2011282100
National Drug Code Directory:0456-3205-60
Patent:WO2011125062
Drugs.com:http://www.drugs.com/cdi/memantine.html
CiteXplore:19196860
Reaxys:6573843
BindingDB:50062599
CASRN:41100-52-1
CiteXplore:20013176
CiteXplore:21213317
ChEMBL:645974
CiteXplore:21875407
PubChem Substance:46506702
Drugs Product Database (DPD):2260638
CiteXplore:21893967
PubChem Compound:4054
PharmGKB:PA10364
DrugBank:DB01043
CiteXplore:20703320
CiteXplore:22214393
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|
| CASRN | 19982-08-2
|
| prefixIRI | obo2:CHEBI_64323
|
| is transported by | |
| SMILES |
Cl.CC12CC3CC(C)(C1)CC(N)(C3)C2
CC12CC3CC(C)(C1)CC(N)(C3)C2
|
| DBname | memantine
|
| InChI |
InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3
InChI=1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H
|
| DBBrand |
ebixa
namenda
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |