The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Id http://purl.obolibrary.org/obo/CHEBI_64312
http://purl.obolibrary.org/obo/CHEBI_64312
Preferred Name

memantine
Synonyms
memantine
memantinum
3,5-dimethyladamantan-1-amine
1,3-Dimethyl-5-adamantanamine
3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
1-Amino-3,5-dimethyladamantane
C12H21N
3,5-Dimethyl-1-adamantanamine
3,5-Dimethyl-1-aminoadamantane
memantina
Type http://www.w3.org/2002/07/owl#Class

All Properties

label
memantine
prefLabel
memantine
blocks
is transported by
Definition
A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.
DBBrand
ebixa
namenda
ATCCode
N06DX01
modulates
SMILES
CC12CC3CC(C)(C1)CC(N)(C3)C2
InChI
InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3
CASRN
19982-08-2
prefixIRI
obo2:CHEBI_64312
altId
CHEBI:34832
Synonym
memantine
memantinum
3,5-dimethyladamantan-1-amine
1,3-Dimethyl-5-adamantanamine
3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
1-Amino-3,5-dimethyladamantane
C12H21N
3,5-Dimethyl-1-adamantanamine
3,5-Dimethyl-1-aminoadamantane
memantina
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binds
has role
DBname
memantine
InChIKey
InChIKey=BUGYDGFZZOZRHP-UHFFFAOYSA-N
subClassOf
inhibits
is substrate of
type
xref
CiteXplore:21955815
CiteXplore:22414570
CiteXplore:22311362
CiteXplore:20104942
CiteXplore:22327556
RxList:http://www.rxlist.com/cgi/generic3/namenda.htm
Wikipedia:http://en.wikipedia.org/wiki/Memantine
KEGG COMPOUND:C13736
CiteXplore:22290557
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/cx1682.shtml
CiteXplore:22425751
ChemSpider:3914
CiteXplore:22245025
KEGG DRUG:D08174
Patent:US2011282100
CiteXplore:22248638
CiteXplore:22030128
CASRN:19982-08-2
National Drug Code Directory:0456-3205-60
CiteXplore:22329473
CiteXplore:22392787
CiteXplore:22134197
CiteXplore:21953515
Drugs.com:http://www.drugs.com/cdi/memantine.html
Reaxys:2075983
CiteXplore:22297273
CiteXplore:22300835
BindingDB:50062599
PubChem Substance:46506702
Drugs Product Database (DPD):2260638
NIST Chemistry WebBook:19982-08-2
ChEMBL:152523
PubChem Compound:4054
PharmGKB:PA10364
DrugBank:DB01043
Wikipedia:Memantine
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DBSynonym
memantine [inn]
memantine hcl
memantinum [inn-latin]
memantina [inn-spanish]
memantine hydrochloride
AHFScode
28:92.00
has pharmacological target
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