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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_64022
http://purl.obolibrary.org/obo/CHEBI_64022
|
|---|---|
| Preferred Name | nebivolol |
| Synonyms |
(1RS,1'RS)-1,1'-[(2RS,2'SR)-bis(6-fluorochroman-2-yl)]-2,2'-iminodiethanol
(1RS,1'RS)-2,2'-iminobis{1-[(2RS,2'SR)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol}
dl-nebivolol
1-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-{[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl]amino}ethan-1-ol
nebivolol
C22H25F2NO4
nebivololum
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | nebivolol
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|---|---|
| label | nebivolol
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| DBSynonym | nebivololum [latin]
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| ATCCode | C07AB12
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| Definition | A racemate consisting of equal amounts of (R,S,S,S)-nebivolol and (S,R,R,R)-nebivolol. A cardioselective beta blocker, it has vasodilatory activity but lacks intrinsic sympathomimetic and membrane-stabilising activity. It is used as the hydrochloride salt for the management of hypertension, and as an adjunct to standard therapy in elderly patients with stable chronic heart failure.
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| has effect |
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| has pharmacological target | |
| type | |
| has role | |
| InChIKey | InChIKey=KOHIRBRYDXPAMZ-UHFFFAOYSA-N
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| is metabolised by | |
| blocks | |
| Synonym | (1RS,1'RS)-1,1'-[(2RS,2'SR)-bis(6-fluorochroman-2-yl)]-2,2'-iminodiethanol
(1RS,1'RS)-2,2'-iminobis{1-[(2RS,2'SR)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol}
dl-nebivolol
1-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-{[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl]amino}ethan-1-ol
nebivolol
C22H25F2NO4
nebivololum
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| xref |
DrugBank:DB04861
PDRhealth:http://www.pdrhealth.com/drugs/rx/rx-mono.aspx?contentFileNam
CASRN:118457-14-0
CiteXplore:18786089
CiteXplore:20620250
PubChem Substance:99443225
Reaxys:4789059
CiteXplore:17661735
ChemSpider:64421
KEGG DRUG:D05127
CiteXplore:18078016
CiteXplore:19443516
Patent:US4654362
Wikipedia:Nebivolol
RxList:http://www.rxlist.com/bystolic-tablets-drug.htm
CiteXplore:18083889
National Drug Code Directory:54868-5944-0
CiteXplore:19815121
PubChem Compound:71301
Drugs.com:http://www.drugs.com/cdi/nebivolol.html
PharmGKB:PA151958426
Wikipedia:http://en.wikipedia.org/wiki/Nebivolol
CiteXplore:18221115
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| CASRN | 99200-09-6
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| prefixIRI | obo2:CHEBI_64022
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| SMILES | OC(CNCC(O)C1CCC2=C(O1)C=CC(F)=C2)C1CCC2=C(O1)C=CC(F)=C2
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| DBname | nebivolol
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| InChI | InChI=1S/C22H25F2NO4/c23-15-3-7-19-13(9-15)1-5-21(28-19)17(26)11-25-12-18(27)22-6-2-14-10-16(24)4-8-20(14)29-22/h3-4,7-10,17-18,21-22,25-27H,1-2,5-6,11-12H2
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| DBBrand |
pi-21858
nodon
nebilet
nebilong
nebicard-5
bystolic
lobivon
nubeta
nebipill
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| subClassOf |
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