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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_63631
http://purl.obolibrary.org/obo/CHEBI_63631
|
|---|---|
| Preferred Name | topiramate |
| Synonyms |
TPM
Topiramate
[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl sulfamate
2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose sulfamate
Topamax
2,3:4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
tipiramate
C12H21NO8S
topiramato
RWJ-17021
tipiramato
topiramatum
topiramate
McN-4853
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | topiramate
|
|---|---|
| label | topiramate
|
| DBSynonym |
tipiramate [french]
topiramatum [inn-latin]
topiramic acid
|
| ATCCode | N03AX11
|
| Definition | A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine.
|
| altId | CHEBI:9633
|
| has effect |
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|
| has pharmacological target | |
| induces | |
| activates | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=KJADKKWYZYXHBB-XBWDGYHZSA-N
|
| blocks | |
| AHFScode | 28:12.92
|
| Synonym | TPM
Topiramate
[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl sulfamate
2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose sulfamate
Topamax
2,3:4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
tipiramate
C12H21NO8S
topiramato
RWJ-17021
tipiramato
topiramatum
topiramate
McN-4853
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See less
|
| xref |
BindingDB:10887
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/top1541.shtml
ChemSpider:4447672
KEGG COMPOUND:C07502
Drugs.com:http://www.drugs.com/cdi/topiramate.html
RxList:http://www.rxlist.com/cgi/generic2/topiram.htm
Drugs Product Database (DPD):2239908
Wikipedia:Topiramate
CASRN:97240-79-4
CiteXplore:22233396
Wikipedia:http://en.wikipedia.org/wiki/Topiramate
ChEMBL:466279
PubChem Substance:46508334
PharmGKB:PA451728
Reaxys:5988957
DrugBank:DB00273
National Drug Code Directory:0904-6016-04
CiteXplore:22249827
KEGG DRUG:D00537
Patent:US4513006
PubChem Compound:5284627
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| CASRN | 97240-79-4
|
| prefixIRI | obo2:CHEBI_63631
|
| SMILES |
CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1
[H][C@@]12CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@@]3([H])[C@]1([H])OC(C)(C)O2
|
| DBname | topiramate
|
| InChI | InChI=1S/C12H21NO8S/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12/h7-9H,5-6H2,1-4H3,(H2,13,14,15)/t7-,8-,9+,12+/m1/s1
|
| DBBrand |
topamax
topamax sprinkle
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
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