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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_63622
http://purl.obolibrary.org/obo/CHEBI_63622
|
|---|---|
| Preferred Name | sotalol |
| Synonyms |
C12H20N2O3S
beta-cardone
sotalol
N-(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenyl)methanesulfonamide
sotalolum
N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide
4'-(1-hydroxy-2-(isopropylamino)ethyl)methane sulfonanilide
Sotalol
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | sotalol
|
|---|---|
| label | sotalol
|
| DBSynonym | sotalol hcl
|
| ATCCode |
C07AA57
C07AA07
|
| Definition | A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is sustituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
|
| altId | CHEBI:9206
|
| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=ZBMZVLHSJCTVON-UHFFFAOYSA-N
|
| blocks | |
| AHFScode | 24:24.00
|
| Synonym |
C12H20N2O3S
beta-cardone
sotalol
N-(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenyl)methanesulfonamide
sotalolum
N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide
4'-(1-hydroxy-2-(isopropylamino)ethyl)methane sulfonanilide
Sotalol
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|
| xref |
KEGG COMPOUND:C07309
PubChem Substance:46505012
ChEMBL:105528
National Drug Code Directory:0245-0012-11
RxList:http://www.rxlist.com/cgi/generic/betapaceaf.htm
Reaxys:2380820
Drugs.com:http://www.drugs.com/cdi/sotalol.html
CiteXplore:21553267
Drugs Product Database (DPD):2257858
CASRN:3930-20-9
KEGG DRUG:D08525
PharmGKB:PA451457
Wikipedia:http://en.wikipedia.org/wiki/Sotalol
CiteXplore:20562595
DrugBank:DB00489
CiteXplore:21854895
BindingDB:25762
Wikipedia:Sotalol
PubChem Compound:5253
ChemSpider:5063
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|
| CASRN | 3930-20-9
|
| prefixIRI | obo2:CHEBI_63622
|
| SMILES |
CC(C)NCC(O)C1=CC=C(NS(C)(=O)=O)C=C1
CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1
|
| DBname | sotalol
|
| InChI | InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3
|
| DBBrand |
betapace
betapace af
sorine
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
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