Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_63619
http://purl.obolibrary.org/obo/CHEBI_63619
|
|---|---|
| Preferred Name | propafenone |
| Synonyms |
propafenona
1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one
propafenone
1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone
C21H27NO3
propafenonum
2-(2'-hydroxy-3'-propylaminopropoxy)-omega-phenylpropiophenone
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | propafenone
|
|---|---|
| label | propafenone
|
| DBSynonym |
propafenona [inn-spanish]
propafenonum [inn-latin]
|
| ATCCode | C01BC03
|
| Definition | A ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
|
| altId | CHEBI:8465
|
| DBSalt | propafenone hydrochloride
|
| has pharmacological target | |
| inhibits |
See more
See less
|
| type | |
| has role | |
| InChIKey | InChIKey=JWHAUXFOSRPERK-UHFFFAOYSA-N
|
| is metabolised by | |
| AHFScode | 24:04.04.12
|
| Synonym |
propafenona
1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one
propafenone
1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone
C21H27NO3
propafenonum
2-(2'-hydroxy-3'-propylaminopropoxy)-omega-phenylpropiophenone
See more
See less
|
| xref |
Guide To Pharmacology:2561
PubChem Substance:46504529
Patent:DE2001431
PharmGKB:PA451131
Reaxys:2175182
Wikipedia:Propafenone
PubChem Compound:4932
CiteXplore:8777484
KEGG COMPOUND:C07381
Drugs Product Database (DPD):2243728
National Drug Code Directory:0173-0786-01
DrugBank:DB01182
ChemSpider:4763
Drugs.com:http://www.drugs.com/cdi/propafenone.html
Wikipedia:http://en.wikipedia.org/wiki/Propafenone
RxList:http://www.rxlist.com/cgi/generic3/propafen.htm
IUPHAR:2561
ChEMBL:127112
KEGG DRUG:D08435
CASRN:54063-53-5
BindingDB:50067133
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/ryt1392.shtml
See more
See less
|
| CASRN | 54063-53-5
|
| prefixIRI | obo2:CHEBI_63619
|
| SMILES |
CCCNCC(O)COC1=CC=CC=C1C(=O)CCC1=CC=CC=C1
CCCNCC(O)COc1ccccc1C(=O)CCc1ccccc1
|
| DBname | propafenone
|
| InChI | InChI=1S/C21H27NO3/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17/h3-11,18,22-23H,2,12-16H2,1H3
|
| DBBrand |
rythmol
rythmol sr
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |