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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_63612
http://purl.obolibrary.org/obo/CHEBI_63612
|
|---|---|
| Preferred Name | nelarabine |
| Synonyms |
Arranon
C11H15N5O5
2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine
(2R,3S,4S,5R)-2-(2-amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
nelzarabine
9-(beta-D-arabinofuranosyl)-6-methoxy-9H-purin-2-amine
Nelzarabine
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | nelarabine
|
|---|---|
| label | nelarabine
|
| DBSynonym |
gw-506u78
nelzarabine
|
| ATCCode | L01BB07
|
| Definition | A purine nucleoside in which O-methylguanine is attached to arabinofuranose via a beta-N(9)-glycosidic bond. Inhibits DNA synthesis and causes cell death; a prodrug of 9-beta-D-arabinofuranosylguanine (ara-G).
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| has effect |
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| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=IXOXBSCIXZEQEQ-UHTZMRCNSA-N
|
| is metabolised by | |
| Synonym |
Arranon
C11H15N5O5
2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine
(2R,3S,4S,5R)-2-(2-amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
nelzarabine
9-(beta-D-arabinofuranosyl)-6-methoxy-9H-purin-2-amine
Nelzarabine
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|
| xref |
CiteXplore:20043113
KEGG DRUG:D06488
CiteXplore:22184539
CiteXplore:21730354
CiteXplore:21190039
CiteXplore:21715318
Wikipedia:http://en.wikipedia.org/wiki/Nelarabine
PubChem Substance:46506325
CiteXplore:20796200
DrugBank:DB01280
ChemSpider:2280207
CiteXplore:18586926
National Drug Code Directory:0007-4401-06
CASRN:121032-29-9
RxList:http://www.rxlist.com/cgi/generic/arranon.htm
Drugs.com:http://www.drugs.com/cdi/nelarabine.html
KEGG DRUG:D05134
CiteXplore:20616909
PubChem Compound:3011155
CiteXplore:21737993
CiteXplore:19825456
Reaxys:13568768
ChEMBL:775063
CiteXplore:20528871
CiteXplore:21151585
CiteXplore:21353591
PharmGKB:PA164752425
CiteXplore:21320002
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| CASRN | 121032-29-9
|
| prefixIRI | obo2:CHEBI_63612
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| related with | |
| SMILES |
COC1=NC(N)=NC2=C1N=CN2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
COc1nc(N)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
|
| DBname | nelarabine
|
| InChI | InChI=1S/C11H15N5O5/c1-20-9-5-8(14-11(12)15-9)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)/t4-,6-,7+,10-/m1/s1
|
| DBBrand |
atriance
arranon (glaxosmithkline)
arranon
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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