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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_63607
http://purl.obolibrary.org/obo/CHEBI_63607
|
|---|---|
| Preferred Name | linezolid |
| Synonyms |
C16H20FN3O4
N-{[(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide
N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide
N-({(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
linezolid
Linezolid
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | linezolid
|
|---|---|
| label | linezolid
|
| ATCCode | J01XX08
|
| Definition | An organofluorine compound that consists of 1,3-oxazolidin-2-one bearing an N-3-fluoro-4-(morpholin-4-yl)phenyl group as well as an acetamidomethyl group at position 5. A synthetic antibacterial agent that inhibits bacterial protein synthesis by binding to a site on 23S ribosomal RNA of the 50S subunit and prevents further formation of a functional 70S initiation complex.
|
| altId | CHEBI:6477
|
| has effect |
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| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=TYZROVQLWOKYKF-ZDUSSCGKSA-N
|
| AHFScode | 08:12.28.24
|
| Synonym |
C16H20FN3O4
N-{[(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide
N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide
N-({(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
linezolid
Linezolid
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| xref |
CiteXplore:22214776
CiteXplore:21815204
BindingDB:50116067
ChEMBL:126280
CiteXplore:21899392
CiteXplore:22064542
CiteXplore:22134348
Patent:WO957271
DrugBank:DB00601
Patent:US5688792
PubChem Substance:46504452
PDB:ZLD
CiteXplore:22110086
ChemSpider:390139
KEGG COMPOUND:C08146
CiteXplore:22037854
CiteXplore:22064533
CASRN:165800-03-3
National Drug Code Directory:0009-5137-01
CiteXplore:22247123
KEGG DRUG:D00947
CiteXplore:22139199
PubChem Compound:441401
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/zyv1556.shtml
PharmGKB:PA450233
CiteXplore:21740298
Reaxys:7496939
Wikipedia:Linezolid
Drugs.com:http://www.drugs.com/cdi/linezolid.html
CiteXplore:22230331
Drugs Product Database (DPD):2243684
Wikipedia:http://en.wikipedia.org/wiki/Linezolid
RxList:http://www.rxlist.com/cgi/generic3/linezolid.htm
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| CASRN | 165800-03-3
|
| prefixIRI | obo2:CHEBI_63607
|
| SMILES |
CC(=O)NC[C@H]1CN(C(=O)O1)C1=CC(F)=C(C=C1)N1CCOCC1
CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(N2CCOCC2)c(F)c1
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| DBname | linezolid
|
| InChI | InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1
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| DBBrand |
zyvox
zyvoxid
linezlid
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |