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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
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| Id | http://purl.obolibrary.org/obo/CHEBI_63577
http://purl.obolibrary.org/obo/CHEBI_63577
|
|---|---|
| Preferred Name | lamivudine |
| Synonyms |
3'-Thia-2',3'-dideoxycytidine
Epivir
Lamivudine
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one
(-)-2'-Deoxy-3'-thiacytidine
beta-L-2',3'-Dideoxy-3'-thiacytidine
C8H11N3O3S
beta-L-3'-Thia-2',3'-dideoxycytidine
2',3'-Dideoxy-3'-thiacytidine
(-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
lamivudine
3TC
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
lamivudine
|
|---|---|
| prefLabel |
lamivudine
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| is metabolised by |
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| is transported by |
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| Definition |
A monothioacetal that consists of cytosine having a (2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl moiety attached at position 1. An inhibitor of HIV-1 reverse transcriptase.
|
| DBBrand |
epivir-hbv
epivir
3tc
zeffix
heptovir
hepitec
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|
| ATCCode |
J05AF05
|
| SMILES |
Nc1ccn([C@@H]2CS[C@H](CO)O2)c(=O)n1
NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
|
| InChI |
InChI=1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m0/s1
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| CASRN |
134678-17-4
|
| prefixIRI |
obo2:CHEBI_63577
|
| altId |
CHEBI:6366
|
| Synonym |
3'-Thia-2',3'-dideoxycytidine
Epivir
Lamivudine
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one
(-)-2'-Deoxy-3'-thiacytidine
beta-L-2',3'-Dideoxy-3'-thiacytidine
C8H11N3O3S
beta-L-3'-Thia-2',3'-dideoxycytidine
2',3'-Dideoxy-3'-thiacytidine
(-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
lamivudine
3TC
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|
| has effect |
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| binds |
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|
| has role | |
| DBname |
lamivudine
|
| InChIKey |
InChIKey=JTEGQNOMFQHVDC-NKWVEPMBSA-N
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| subClassOf | |
| may interact with | |
| inhibits | |
| related with | |
| is substrate of |
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| type | |
| xref |
CiteXplore:22233654
ChEBI:63577
KEGG COMPOUND:C07065
CiteXplore:22211086
CiteXplore:21851334
Wikipedia:http://en.wikipedia.org/wiki/Lamivudine
CiteXplore:22231575
BindingDB:50046287
National Drug Code Directory:0173-0742-00
CiteXplore:22028068
CiteXplore:22222724
RxList:http://www.rxlist.com/cgi/generic3/lamivudine.htm
Drugs Product Database (DPD):2239194
CASRN:134678-17-4
CiteXplore:21721935
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/com1513.shtml
PharmGKB:PA450163
CiteXplore:22098177
ChemSpider:54812
PubChem Substance:46507855
Patent:WO9117159
KEGG DRUG:D00353
Reaxys:5480511
Drugs.com:http://www.drugs.com/cdi/lamivudine.html
Wikipedia:Lamivudine
CiteXplore:22170540
PubChem Compound:60825
CiteXplore:22085635
CiteXplore:22078148
ChEMBL:133986
CiteXplore:22001270
CiteXplore:21465499
CiteXplore:22097898
DrugBank:DB00709
CiteXplore:22226087
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| AHFScode |
08:18.08.20
|
| has pharmacological target |
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