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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_59582
http://purl.obolibrary.org/obo/CHEBI_59582
|
|---|---|
| Preferred Name | clocortolone |
| Synonyms |
C22H28ClFO4
9-chloro-6alpha-fluoro-16alpha-methyl-1,4-pregnadiene-11beta,21-diol-3,20-dione
(1R,2S,8S,10S,11S,13R,14S,15S,17S)-1-chloro-8-fluoro-17-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
clocortolone
9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
clocortolonum
clocortolona
9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methyl-1,4-pregnadien-3,20-dione
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | clocortolone
|
|---|---|
| label | clocortolone
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| DBSynonym | clocortolone pivalate
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| ATCCode | D07AB21
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| Definition | 16alpha-Methylpregna-1,4-diene-3,20-dione bearing hydroxy substituents at the 11beta and 21 positions, fluorine at position 6 and chlorine at position 9. A medium potency corticosteroid, it is used as its 21-O-pivalate or caproate ester for the relief of inflammatory and pruritic (itching) skin disorders.
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| has effect | |
| has pharmacological target | |
| activates | |
| type | |
| has role | |
| InChIKey | InChIKey=YMTMADLUXIRMGX-RFPWEZLHSA-N
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| Synonym | C22H28ClFO4
9-chloro-6alpha-fluoro-16alpha-methyl-1,4-pregnadiene-11beta,21-diol-3,20-dione
(1R,2S,8S,10S,11S,13R,14S,15S,17S)-1-chloro-8-fluoro-17-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
clocortolone
9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
clocortolonum
clocortolona
9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methyl-1,4-pregnadien-3,20-dione
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| xref |
PharmGKB:PA164744013
KEGG DRUG:D07719
CASRN:4828-27-7
Beilstein:6318064
Wikipedia:Clocortolone
ChEMBL:775317
Patent:DE2011559
Drugs.com:http://www.drugs.com/cdi/clocortolone.html
RxList:http://www.rxlist.com/cgi/generic2/clocortolone.htm
Patent:NL6412708
Patent:US3729495
Wikipedia:http://en.wikipedia.org/wiki/Clocortolone
ChEBI:59582
DrugBank:DB00838
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| CASRN | 34097-16-0
|
| prefixIRI | obo2:CHEBI_59582
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| SMILES | [H][C@@]12C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(Cl)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C
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| may interact with | |
| DBname | clocortolone
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| InChI | InChI=1S/C22H28ClFO4/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-21(15,3)22(14,23)18(28)9-20(13,2)19(11)17(27)10-25/h4-5,7,11,13-14,16,18-19,25,28H,6,8-10H2,1-3H3/t11-,13+,14+,16+,18+,19-,20+,21+,22+/m1/s1
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| DBBrand | cloderm
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| subClassOf |
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