loading...| Preferred Name | gonadorelin | |
| Synonyms |
Follicle-stimulating hormone-releasing factor LH-Releasing hormone C55H75N17O13 5-oxo-PHWSYGLRPGNH2 gonadorelina p-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 LH-Releasing factor Luteinizing hormone-releasing factor GnRH-I 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-L-prolylglycinamide gonadorelin Gonadotropin-releasing factor gonadorelinum N-(1-{2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl}-5-[(diaminomethylidene)amino]-1-oxopentan-2-yl)-2-{2-[2-(3-hydroxy-2-{2-[3-(1H-imidazol-5-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]-3-(1H-indol-3-yl)propanamido}propanamido)-3-(4-hydroxyphenyl)propanamido]acetamido}-4-methylpentanamide Gonadotropin-releasing hormone I Gonadoliberin I luliberin |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_5520 |
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| activates | ||
| AHFScode |
68:18.00 |
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| ATCCode |
H01CA01 V04CM01 |
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| binds | ||
| CASRN |
6918-09-8 |
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| DBBrand |
gonadorelinum [inn-latin] synthetic decapeptide fsh/lh-rh synthetic lh-fsh releasing hormone dirigestran relisorm l human lh-rh hypocrine lutrepulse mammalian gnrh dirigestran spofa lutal relefact fertagyl gonadorelina [inn-spanish] lutrepulse kit synthetic gonadoliberin synthetic gn-rh luforan mammalian lh-rh synthetic lh-releasing factor gonadotropin-releasing hormone porchine lh-rh synthetic lh-rh porcine lh-releasing factor relisorm synthetic lrf gonadotropin-releasing factor lutrefact synthetic lh-releasing hormone synthetic lh-rf factrel lutamin gonadotropin releasing hormone ovine lh-rh |
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| DBname |
gonadorelin |
|
| Definition |
A ten-membered synthetic oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, glycyl, leucyl, arginyl, prolyl and glycinamide residues joined in sequence. |
|
| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C55H75N17O13/c1-29(2)19-38(49(80)67-37(9-5-17-60-55(57)58)54(85)72-18-6-10-43(72)53(84)62-25-44(56)75)66-46(77)26-63-47(78)39(20-30-11-13-33(74)14-12-30)68-52(83)42(27-73)71-50(81)40(21-31-23-61-35-8-4-3-7-34(31)35)69-51(82)41(22-32-24-59-28-64-32)70-48(79)36-15-16-45(76)65-36/h3-4,7-8,11-14,23-24,28-29,36-43,61,73-74H,5-6,9-10,15-22,25-27H2,1-2H3,(H2,56,75)(H,59,64)(H,62,84)(H,63,78)(H,65,76)(H,66,77)(H,67,80)(H,68,83)(H,69,82)(H,70,79)(H,71,81)(H4,57,58,60) InChI=1S/C55H75N17O13/c1-29(2)19-38(49(80)67-37(9-5-17-60-55(57)58)54(85)72-18-6-10-43(72)53(84)62-25-44(56)75)66-46(77)26-63-47(78)39(20-30-11-13-33(74)14-12-30)68-52(83)42(27-73)71-50(81)40(21-31-23-61-35-8-4-3-7-34(31)35)69-51(82)41(22-32-24-59-28-64-32)70-48(79)36-15-16-45(76)65-36/h3-4,7-8,11-14,23-24,28-29,36-43,61,73-74H,5-6,9-10,15-22,25-27H2,1-2H3,(H2,56,75)(H,59,64)(H,62,84)(H,63,78)(H,65,76)(H,66,77)(H,67,80)(H,68,83)(H,69,82)(H,70,79)(H,71,81)(H4,57,58,60)/t36-,37-,38-,39-,40-,41-,42-,43-/m0/s1 |
|
| InChIKey |
InChIKey=XLXSAKCOAKORKW-UHFFFAOYSA-N InChIKey=XLXSAKCOAKORKW-AQJXLSMYSA-N |
|
| label |
gonadorelin |
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| modulates | ||
| prefixIRI |
obo2:CHEBI_5520 |
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| prefLabel |
gonadorelin |
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| SMILES |
CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O CC(C)CC(NC(=O)CNC(=O)C(CC1=CC=C(O)C=C1)NC(=O)C(CO)NC(=O)C(CC1=CNC2=CC=CC=C12)NC(=O)C(CC1=CN=CN1)NC(=O)C1CCC(=O)N1)C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NCC(N)=O |
|
| Synonym |
Follicle-stimulating hormone-releasing factor LH-Releasing hormone C55H75N17O13 5-oxo-PHWSYGLRPGNH2 gonadorelina p-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 LH-Releasing factor Luteinizing hormone-releasing factor GnRH-I 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-L-prolylglycinamide gonadorelin Gonadotropin-releasing factor gonadorelinum N-(1-{2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl}-5-[(diaminomethylidene)amino]-1-oxopentan-2-yl)-2-{2-[2-(3-hydroxy-2-{2-[3-(1H-imidazol-5-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]-3-(1H-indol-3-yl)propanamido}propanamido)-3-(4-hydroxyphenyl)propanamido]acetamido}-4-methylpentanamide Gonadotropin-releasing hormone I Gonadoliberin I luliberin |
|
| xref |
ChEMBL:212560 CiteXplore:22504307 DrugBank:DB00644 Wikipedia:http://en.wikipedia.org/wiki/Gonadorelin KEGG DRUG:D08027 CiteXplore:21872303 CiteXplore:22761896 Drugs.com:http://www.drugs.com/cdi/gonadorelin.html PubChem Substance:46506144 RxList:http://www.rxlist.com/cgi/generic2/gonadorelin.htm PubChem Compound:36523 PharmGKB:PA449801 CiteXplore:22214466 Drugs Product Database (DPD):573760 Wikipedia:Gonadorelin CiteXplore:22112812 Reaxys:741807 ChemSpider:33562 CASRN:33515-09-2 CiteXplore:22289217 KEGG COMPOUND:C07607 |
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| subClassOf |