The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

alfuzosin
Synonyms

alfuzosin

N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}oxolane-2-carboxamide

alfuzosine

alfuzosinum

N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}tetrahydrofuran-2-carboxamide

C19H27N5O4

alfuzosina
ID

http://purl.obolibrary.org/obo/CHEBI_51141
AHFScode

92:00.00
ATCCode

G04CA01
binds

http://purl.obolibrary.org/obo/dinto_4020

http://purl.obolibrary.org/obo/dinto_3475

http://purl.obolibrary.org/obo/dinto_0234

http://purl.obolibrary.org/obo/dinto_0901
blocks

http://purl.obolibrary.org/obo/dinto_4020

http://purl.obolibrary.org/obo/dinto_3475

http://purl.obolibrary.org/obo/dinto_0234
CASRN

81403-80-7
DBBrand

xatral

uroxatral
DBname

alfuzosin
DBSynonym

alfusosine
Definition

A tetrahydrofuranol that has formula C19H27N5O4.
has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0001373

http://purl.obolibrary.org/obo/OAE_0000236

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000839

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000659

http://purl.obolibrary.org/obo/OAE_0000596

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0000493

http://purl.obolibrary.org/obo/OAE_0000443

http://purl.obolibrary.org/obo/OAE_0000921

http://purl.obolibrary.org/obo/OAE_0001369

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000418

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0000660

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000551

http://purl.obolibrary.org/obo/OAE_0000455

http://purl.obolibrary.org/obo/OAE_0001737

http://purl.obolibrary.org/obo/OAE_0000502

http://purl.obolibrary.org/obo/OAE_0000084

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0001135

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000789

http://purl.obolibrary.org/obo/OAE_0001164

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0002122

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000514

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000462

http://purl.obolibrary.org/obo/OAE_0000358

http://purl.obolibrary.org/obo/OAE_0001366

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000350
has pharmacological target

http://purl.obolibrary.org/obo/dinto_4020

http://purl.obolibrary.org/obo/dinto_3475

http://purl.obolibrary.org/obo/dinto_0234
has role

http://purl.obolibrary.org/obo/CHEBI_35610

http://purl.obolibrary.org/obo/CHEBI_37890

http://purl.obolibrary.org/obo/CHEBI_35674
InChI

InChI=1S/C19H27N5O4/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(27-3)15(26-2)10-12(13)17(20)23-19/h10-11,14H,4-9H2,1-3H3,(H,21,25)(H2,20,22,23)
InChIKey

InChIKey=WNMJYKCGWZFFKR-UHFFFAOYSA-N
is metabolised by

http://purl.obolibrary.org/obo/dinto_0901
is substrate of

http://purl.obolibrary.org/obo/dinto_0901
label

alfuzosin
may interact with

http://purl.obolibrary.org/obo/CHEBI_71940

http://purl.obolibrary.org/obo/CHEBI_68621

http://purl.obolibrary.org/obo/CHEBI_68595

http://purl.obolibrary.org/obo/dinto_DB01167

http://purl.obolibrary.org/obo/CHEBI_681850

http://purl.obolibrary.org/obo/CHEBI_9445

http://purl.obolibrary.org/obo/dinto_DB00582

http://purl.obolibrary.org/obo/CHEBI_9398

http://purl.obolibrary.org/obo/dinto_DB00503

http://purl.obolibrary.org/obo/dinto_DB01026

http://purl.obolibrary.org/obo/CHEBI_46295

http://purl.obolibrary.org/obo/dinto_DB00976
modulates

http://purl.obolibrary.org/obo/dinto_4020

http://purl.obolibrary.org/obo/dinto_3475

http://purl.obolibrary.org/obo/dinto_0234
prefixIRI

obo2:CHEBI_51141
prefLabel

alfuzosin
SMILES

COC1=C(OC)C=C2C(N)=NC(=NC2=C1)N(C)CCCNC(=O)C1CCCO1

COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C1CCCO1
Synonym

alfuzosin

N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}oxolane-2-carboxamide

alfuzosine

alfuzosinum

N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}tetrahydrofuran-2-carboxamide

C19H27N5O4

alfuzosina
xref

CASRN:81403-80-7

Patent:DE2904445

RxList:http://www.rxlist.com/cgi/generic/uroxatral.htm

PubChem Substance:46508512

PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/uro1685.shtml

PubChem Compound:2092

Patent:US4315007

KEGG DRUG:D07124

Drugs Product Database (DPD):2245565

Drugs.com:http://www.drugs.com/cdi/alfuzosin.html

ChemSpider:2008

ChEMBL:133667

National Drug Code Directory:0024-4200-30

Wikipedia:http://en.wikipedia.org/wiki/Alfuzosin

ChEBI:51141

DrugBank:DB00346

Wikipedia:Alfuzosin

PharmGKB:PA164774795
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_51141 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_51141 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_51141 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_51141 DDSS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_51141 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_51141 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_51141 NIFSTD SAME_URI
http://purl.bioontology.org/ontology/RCD/x01CM RCD LOOM
http://www.phoc.org.cn/pmo/class/PMO_00025811 PMAPP-PMO LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Alfuzosin STMSO LOOM
https://go.drugbank.com/drugs/DB00346 MDM LOOM
http://purl.bioontology.org/ontology/MESH/C047638 MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148814 NDFRT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#13445 OCHV LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148814 OCVDAE LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61627 NCIT LOOM
http://www.drugbank.ca/drugs/DB00346 FTC LOOM
http://purl.jp/bio/4/id/200906093544603323 IOBC LOOM
http://purl.obolibrary.org/obo/NCIT_C61627 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_51141 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_51141 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_51141 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_51141 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_51141 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_51141 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_51141 NIFSTD LOOM
http://purl.bioontology.org/ontology/NDDF/005431 NDDF LOOM
http://purl.bioontology.org/ontology/VANDF/4021396 VANDF LOOM
http://purl.bioontology.org/ontology/ATC/G04CA01 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/395954002 SNOMEDCT LOOM
http://stirdf.jst.go.jp/id/200907086069834410 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/17300 RXNORM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0051150 OCHV LOOM
http://www.co-ode.org/ontologies/galen#Alfuzosin GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C047638 RH-MESH LOOM