The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Id http://purl.obolibrary.org/obo/CHEBI_50305
http://purl.obolibrary.org/obo/CHEBI_50305
Preferred Name

podophyllotoxin
Synonyms
Podophyllinic acid lactone
Condylox
9-HYDROXY-5-(3,4,5-TRIMETHOXYPHENYL)-5,8,8A,9-TETRAHYDROFURO[3',4':6,7]NAPHTHO[2,3-D][1,3]DIOXOL-6(5AH)-ONE
PPT
C22H22O8
(10R,11R,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9),2,7-trien-12-one
(5R,5aR,8aR,9R)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one
(-)-podophyllotoxin
Podofilox
Podophyllotoxin
Podophyllotoxin 7
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Type http://www.w3.org/2002/07/owl#Class

All Properties

label
podophyllotoxin
prefLabel
podophyllotoxin
is metabolised by
Definition
An organic heterotetracyclic compound that has a furonaphthodioxole skeleton bearing a 3,4,5-trimethoxyphenyl substituent. It is found in the roots and rhizomes of Podophyllum species and is used for the topical treatment of genital warts.
DBBrand
podophyllotoxin
podophyllotoxin 7
ATCCode
D06BB04
SMILES
[H][C@]12COC(=O)[C@]1([H])[C@H](c1cc(OC)c(OC)c(OC)c1)c1cc3OCOc3cc1[C@@H]2O
[H][C@]12COC(=O)[C@]1([H])[C@H](C1=CC(OC)=C(OC)C(OC)=C1)C1=CC3=C(OCO3)C=C1[C@@H]2O
InChI
InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1
CASRN
477-47-4
prefixIRI
obo2:CHEBI_50305
altId
CHEBI:45070
CHEBI:8280
Synonym
Podophyllinic acid lactone
Condylox
9-HYDROXY-5-(3,4,5-TRIMETHOXYPHENYL)-5,8,8A,9-TETRAHYDROFURO[3',4':6,7]NAPHTHO[2,3-D][1,3]DIOXOL-6(5AH)-ONE
PPT
C22H22O8
(10R,11R,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9),2,7-trien-12-one
(5R,5aR,8aR,9R)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one
(-)-podophyllotoxin
Podofilox
Podophyllotoxin
Podophyllotoxin 7
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binds
has role
DBname
podofilox
InChIKey
InChIKey=YJGVMLPVUAXIQN-XVVDYKMHSA-N
subClassOf
inhibits
is substrate of
type
xref
Drugs.com:http://www.drugs.com/cdi/podofilox-gel.html
CiteXplore:8112825
RxList:http://www.rxlist.com/cgi/generic4/podophyllin.htm
CiteXplore:22621772
Reaxys:99163
National Drug Code Directory:0574-0611-05
PharmGKB:PA450993
ChEBI:50305
CASRN:518-28-5
PubChem Substance:46505716
ChEMBL:104775
Wikipedia:Podophyllotoxin
HMDB:HMDB31452
CiteXplore:23798883
PubChem Compound:10607
CiteXplore:23161544
ChemSpider:10162
Wikipedia:http://en.wikipedia.org/wiki/Podofilox
DrugBank:DB01179
KEGG DRUG:D05529
PDBeChem:POD
KEGG COMPOUND:C10874
CiteXplore:15803102
PDB:POD
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DBSynonym
podophyllinic acid lactone
AHFScode
84:92.00
has pharmacological target
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