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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_49603
http://purl.obolibrary.org/obo/CHEBI_49603
|
|---|---|
| Preferred Name | lapatinib |
| Synonyms |
N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine
C29H26ClFN4O4S
N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE
N-[3-chloro-4-(3-fluorobenzyloxy)phenyl]-6-[5-({[2-(methanesulfonyl)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine
N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine
GW 572016
Tykerb
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | lapatinib
|
|---|---|
| label | lapatinib
|
| DBSynonym |
gw 572016
lapatinib tosilate hydrate
gw572016
lapatinib ditosylate
fmm
|
| ATCCode | L01XE07
|
| Definition | A quinazoline that has formula C29H26ClFN4O4S.
|
| altId |
CHEBI:38636
CHEBI:49602
|
| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=BCFGMOOMADDAQU-UHFFFAOYSA-N
|
| is metabolised by | |
| blocks | |
| Synonym | N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine
C29H26ClFN4O4S
N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE
N-[3-chloro-4-(3-fluorobenzyloxy)phenyl]-6-[5-({[2-(methanesulfonyl)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine
N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine
GW 572016
Tykerb
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|
| xref |
PubChem Compound:208908
Drugs.com:http://www.drugs.com/cdi/lapatinib.html
PDB:FMM
PharmGKB:PA152241907
ChEMBL:114805
CASRN:231277-92-2
Wikipedia:Lapatinib
RxList:http://www.rxlist.com/cgi/generic/tykerb.htm
Beilstein:10502247
BindingDB:5445
ChEBI:49603
National Drug Code Directory:0173-0752-00
PubChem Substance:46507141
Wikipedia:http://en.wikipedia.org/wiki/Lapatinib
ChemSpider:181006
DrugBank:DB01259
PDBeChem:FMM
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|
| CASRN | 388082-78-8
|
| prefixIRI | obo2:CHEBI_49603
|
| SMILES |
CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1
CS(=O)(=O)CCNCC1=CC=C(O1)C1=CC2=C(C=C1)N=CN=C2NC1=CC(Cl)=C(OCC2=CC(F)=CC=C2)C=C1
|
| may interact with |
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| DBname | lapatinib
|
| InChI | InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)
|
| DBBrand |
tycerb
tykerb
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
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