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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_4953
http://purl.obolibrary.org/obo/CHEBI_4953
|
|---|---|
| Preferred Name | exemestane |
| Synonyms |
Exemestane
6-methyleneandrosta-1,4-diene-3,17-dione
6-methylideneandrosta-1,4-diene-3,17-dione
C20H24O2
exemestane
exemestanum
(1S,2R,10R,11S,15S)-2,15-dimethyl-8-methylidenetetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,14-dione
exemestano
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | exemestane
|
|---|---|
| label | exemestane
|
| DBSynonym |
exemestanum [inn-latin]
exemestano [inn-spanish]
|
| ATCCode | L02BG06
|
| Definition | A 17-oxo steroid that is androsta-1,4-diene-3,17-dione in which the hydrogens at position 6 are replaced by a double bond to a methylene group. A selective inhibitor of the aromatase (oestrogen synthase) system, it is used in the treatment of advanced breast cancer.
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| has effect |
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| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=BFYIZQONLCFLEV-DAELLWKTSA-N
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| is metabolised by | |
| AHFScode | 10:00.00
|
| Synonym | Exemestane
6-methyleneandrosta-1,4-diene-3,17-dione
6-methylideneandrosta-1,4-diene-3,17-dione
C20H24O2
exemestane
exemestanum
(1S,2R,10R,11S,15S)-2,15-dimethyl-8-methylidenetetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,14-dione
exemestano
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|
| xref |
PubChem Compound:60198
Drugs Product Database (DPD):2242705
Wikipedia:Exemestane
RxList:http://www.rxlist.com/cgi/generic3/exemest.htm
National Drug Code Directory:0009-7663-04
ChEMBL:774325
CiteXplore:10882163
KEGG COMPOUND:C08162
PharmGKB:PA449563
CASRN:107868-30-4
KEGG DRUG:D00963
Wikipedia:http://en.wikipedia.org/wiki/Exemestane
ChemSpider:54278
PubChem Substance:46508243
ChEBI:4953
Drugs.com:http://www.drugs.com/cdi/exemestane.html
DrugBank:DB00990
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| CASRN | 107868-30-4
|
| prefixIRI | obo2:CHEBI_4953
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| SMILES |
[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC(=C)C2=CC(=O)C=C[C@]12C
[H][C@@]12CC(=C)C3=CC(=O)C=C[C@]3(C)[C@@]1([H])CC[C@]1(C)C(=O)CC[C@@]21[H]
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| DBname | exemestane
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| InChI | InChI=1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1
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| DBBrand |
exemestance
aromasin
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| subClassOf |
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