The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_49040 http://purl.obolibrary.org/obo/CHEBI_49040
Preferred Name	ezetimibe
Synonyms	Zetia Ezedoc ezetimiba (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one ezetimibum ezetimibe Ezetrol C24H21F2NO3
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	ezetimibe
label	ezetimibe
ATCCode	C10AX09
Definition	A beta-lactam that is azetidin-2-one which is substituted at 1, 3, and 4 by p-fluorophenyl, 3-(p-fluorophenyl)-3-hydroxypropyl, and 4-hydroxyphenyl groups, respectively (the 3R,3'S,4S enantiomer).
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0001373 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000839 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0001369 http://purl.obolibrary.org/obo/OAE_0000567 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0001378 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000525 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000022 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000336 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000466 http://purl.obolibrary.org/obo/OAE_0000358 http://purl.obolibrary.org/obo/OAE_0000402 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2885 http://purl.obolibrary.org/obo/dinto_2775
inhibits	http://purl.obolibrary.org/obo/dinto_2885 http://purl.obolibrary.org/obo/dinto_2775 http://purl.obolibrary.org/obo/dinto_0901
type	http://www.w3.org/2002/07/owl#Class
has role	http://purl.obolibrary.org/obo/CHEBI_35679 http://purl.obolibrary.org/obo/CHEBI_35821 http://purl.obolibrary.org/obo/CHEBI_35221
InChIKey	InChIKey=OLNTVTPDXPETLC-XPWALMASSA-N
is metabolised by	http://purl.obolibrary.org/obo/dinto_1890 http://purl.obolibrary.org/obo/dinto_1892 http://purl.obolibrary.org/obo/dinto_1711 http://purl.obolibrary.org/obo/dinto_0276
AHFScode	24:06.05
Synonym	Zetia Ezedoc ezetimiba (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one ezetimibum ezetimibe Ezetrol C24H21F2NO3 See more See less
xref	RxList:http://www.rxlist.com/cgi/generic/ezetimibe.htm PubChem Substance:46507625 DrugBank:DB00973 CiteXplore:23317398 CiteXplore:23510093 Drugs Product Database (DPD):2247521 Reaxys:7981967 CiteXplore:23538020 ChemSpider:132493 CiteXplore:18585981 Beilstein:7981967 ChEMBL:275106 PubChem Compound:150311 HMDB:HMDB15108 CiteXplore:23471229 CiteXplore:23266293 Wikipedia:Ezetimibe CiteXplore:17587760 PharmGKB:PA10816 KEGG DRUG:D01966 Drugs.com:http://www.drugs.com/ezetimibe.html CASRN:163222-33-1 Wikipedia:http://en.wikipedia.org/wiki/Ezetimibe CiteXplore:23219178 National Drug Code Directory:66582-414-31 ChEBI:49040 See more See less
CASRN	163222-33-1
prefixIRI	obo2:CHEBI_49040
is transported by	http://purl.obolibrary.org/obo/dinto_0588 http://purl.obolibrary.org/obo/dinto_0887 http://purl.obolibrary.org/obo/dinto_0883 http://purl.obolibrary.org/obo/dinto_1560 http://purl.obolibrary.org/obo/dinto_1561 http://purl.obolibrary.org/obo/dinto_2019 http://purl.obolibrary.org/obo/dinto_1440 See more See less
related with	http://purl.obolibrary.org/obo/dinto_0822
SMILES	[H][C@]1(CC[C@H](O)c2ccc(F)cc2)C(=O)N(c2ccc(F)cc2)[C@]1([H])c1ccc(O)cc1 O[C@@H](CC[C@@H]1[C@H](N(C1=O)C1=CC=C(F)C=C1)C1=CC=C(O)C=C1)C1=CC=C(F)C=C1
may interact with	http://purl.obolibrary.org/obo/CHEBI_4031 http://purl.obolibrary.org/obo/CHEBI_10033 http://purl.obolibrary.org/obo/dinto_DB01432
DBname	ezetimibe
InChI	InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1
DBBrand	ezedoc zient zetia maxetibe zetavim zemitra ezetib ezetrol See more See less
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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