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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_4788
http://purl.obolibrary.org/obo/CHEBI_4788
|
|---|---|
| Preferred Name | encainide |
| Synonyms |
(+-)-2'-[2-(1-methyl-2-piperidyl)ethyl]-p-anisanilide
Encainide
(+-)-4-methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide
encainide
4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide
C22H28N2O2
4-Methoxy-N-{2-[2-(1-methyl-piperidin-2-yl)-ethyl]-phenyl}-benzamide
encainida
encainidum
4-methoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | encainide
|
|---|---|
| label | encainide
|
| DBSynonym |
encainide [french]
encainida [spanish]
encainidum [latin]
|
| ATCCode | C01BC08
|
| Definition | 4-Methoxy-N-phenylbenzamide in which the hydrogen at the 2 position of the phenyl group is substituted by a 2-(1-methylpiperidin-2-yl)ethyl group. A class Ic antiarrhythmic, the hydrochloride was used for the treatment of severe or life-threatening ventricular arrhythmias, but it was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack and was withdrawn from the market.
|
| altId | CHEBI:239046
|
| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=PJWPNDMDCLXCOM-UHFFFAOYSA-N
|
| is metabolised by | |
| Synonym |
(+-)-2'-[2-(1-methyl-2-piperidyl)ethyl]-p-anisanilide
Encainide
(+-)-4-methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide
encainide
4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide
C22H28N2O2
4-Methoxy-N-{2-[2-(1-methyl-piperidin-2-yl)-ethyl]-phenyl}-benzamide
encainida
encainidum
4-methoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide
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|
| xref |
ChEBI:4788
KEGG COMPOUND:C06978
PharmGKB:PA449459
DrugBank:DB01228
Patent:US3931195
KEGG DRUG:D07894
Patent:DE2210154
Beilstein:497572
CASRN:66778-36-7
National Drug Code Directory:0087-0732-41
Wikipedia:http://en.wikipedia.org/wiki/Encainide
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|
| CASRN | 66778-36-7
|
| prefixIRI | obo2:CHEBI_4788
|
| SMILES |
COC1=CC=C(C=C1)C(=O)NC1=CC=CC=C1CCC1CCCCN1C
COc1ccc(cc1)C(=O)Nc1ccccc1CCC1CCCCN1C
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| may interact with | |
| DBname | encainide
|
| InChI | InChI=1S/C22H28N2O2/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(25)18-11-14-20(26-2)15-12-18/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,16H2,1-2H3,(H,23,25)
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| DBBrand | enkaid
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |