The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_4779 http://purl.obolibrary.org/obo/CHEBI_4779
Preferred Name	emedastine
Synonyms	emedastinum 1-(2-Ethoxy-ethyl)-2-(4-methyl-[1,4]diazepan-1-yl)-1H-benzoimidazole 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzimidazole emedastina Emedastine emedastine C17H26N4O EMEDASTINE 1-[2-(ethoxy)ethyl]-2-(4-methyl-1-homopiperazinyl)benzimidazole 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole See more See less
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	emedastine
label	emedastine
DBSynonym	emedastinum [inn-latin] emedastina [inn-spanish] emedastine difumarate
ATCCode	S01GX06
Definition	1-Methyl-1,4-diazepane in which the hydrogen attached to the nitrogen at position 4 is substituted by a 1-(2-ethoxyethyl)-1H-benzimidazol-2-yl group. A relatively selective histamine H1 antagonist, it is used as the difumatate salt for allergic rhinitis, urticaria, and pruritic skin disorders, and in eyedrops for the symptomatic relief of allergic conjuntivitis.
altId	CHEBI:119712
has effect	http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000567 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000350 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_1071
type	http://www.w3.org/2002/07/owl#Class
has role	http://purl.obolibrary.org/obo/CHEBI_37955 http://purl.obolibrary.org/obo/CHEBI_59683 http://purl.obolibrary.org/obo/CHEBI_50857
InChIKey	InChIKey=KBUZBQVCBVDWKX-UHFFFAOYSA-N
blocks	http://purl.obolibrary.org/obo/dinto_1071
AHFScode	52:02.00
Synonym	emedastinum 1-(2-Ethoxy-ethyl)-2-(4-methyl-[1,4]diazepan-1-yl)-1H-benzoimidazole 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzimidazole emedastina Emedastine emedastine C17H26N4O EMEDASTINE 1-[2-(ethoxy)ethyl]-2-(4-methyl-1-homopiperazinyl)benzimidazole 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole See more See less
xref	BindingDB:50019624 Wikipedia:Emedastine Beilstein:6068161 Wikipedia:http://en.wikipedia.org/wiki/Emedastine National Drug Code Directory:0065-0325-05 ChemSpider:3106 PubChem Compound:3219 Drugs Product Database (DPD):2237355 PubChem Substance:46505109 KEGG COMPOUND:C07785 PharmGKB:PA164751802 Patent:US4430343 KEGG DRUG:D07890 CASRN:87233-61-2 ChEBI:4779 Drugs.com:http://www.drugs.com/mtm/emedastine-ophthalmic.html DrugBank:DB01084 RxList:http://www.rxlist.com/cgi/generic2/emedastine.htm See more See less
CASRN	87233-61-2
prefixIRI	obo2:CHEBI_4779
SMILES	CCOCCN1C(=NC2=CC=CC=C12)N1CCCN(C)CC1 CCOCCn1c(nc2ccccc12)N1CCCN(C)CC1
DBname	emedastine
InChI	InChI=1S/C17H26N4O/c1-3-22-14-13-21-16-8-5-4-7-15(16)18-17(21)20-10-6-9-19(2)11-12-20/h4-5,7-8H,3,6,9-14H2,1-2H3
DBBrand	emadine
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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