The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_47544 http://purl.obolibrary.org/obo/CHEBI_47544
Preferred Name	loracarbef
Synonyms	C16H16ClN3O4 LORACABEF (6R,7S)-7-[(2R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (6R,7S)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid loracarbef 7beta-[(2R)-2-amino-2-phenylacetyl]nitrilo-3-chloro-3,4-didehydrocepham-4-carboxylic acid loracarbefum
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	loracarbef
label	loracarbef
DBSynonym	loracarbefum [inn-latin]
ATCCode	J01DC08
Definition	A synthetic "carba" analogue of cefaclor, with carbon replacing sulfur at position 1. Used to treat a wide range of infections caused by both gram-positive and gram-negative bacteria.
has pharmacological target	http://purl.obolibrary.org/obo/dinto_3289 http://purl.obolibrary.org/obo/dinto_4015
inhibits	http://purl.obolibrary.org/obo/dinto_3289 http://purl.obolibrary.org/obo/dinto_4015 http://purl.obolibrary.org/obo/dinto_4065 http://purl.obolibrary.org/obo/dinto_2004
type	http://www.w3.org/2002/07/owl#Class
has role	http://purl.obolibrary.org/obo/CHEBI_22582 http://purl.obolibrary.org/obo/CHEBI_36047
InChIKey	InChIKey=JAPHQRWPEGVNBT-UTUOFQBUSA-N
Synonym	C16H16ClN3O4 LORACABEF (6R,7S)-7-[(2R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (6R,7S)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid loracarbef 7beta-[(2R)-2-amino-2-phenylacetyl]nitrilo-3-chloro-3,4-didehydrocepham-4-carboxylic acid loracarbefum See more See less
xref	PharmGKB:PA164754806 CASRN:76470-66-1 Wikipedia:http://en.wikipedia.org/wiki/Loracarbef Patent:EP14476 PDBeChem:LOR RxList:http://www.rxlist.com/cgi/generic/loracarb.htm DrugBank:DB00447 Drugs.com:http://www.drugs.com/cdi/loracarbef.html CiteXplore:9131470 Patent:US4708956 KEGG DRUG:D08143 Beilstein:3631282 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/lor1237.shtml National Drug Code Directory:61570-170-01 ChEBI:47544 See more See less
CASRN	76470-66-1
prefixIRI	obo2:CHEBI_47544
SMILES	N[C@@H](C(=O)N[C@H]1[C@H]2CCC(Cl)=C(N2C1=O)C(O)=O)C1=CC=CC=C1 N[C@@H](C(=O)N[C@H]1[C@H]2CCC(Cl)=C(N2C1=O)C(O)=O)c1ccccc1
may interact with	http://purl.obolibrary.org/obo/CHEBI_8426
DBname	loracarbef
InChI	InChI=1S/C16H16ClN3O4/c17-9-6-7-10-12(15(22)20(10)13(9)16(23)24)19-14(21)11(18)8-4-2-1-3-5-8/h1-5,10-12H,6-7,18H2,(H,19,21)(H,23,24)/t10-,11-,12+/m1/s1
DBBrand	loribid lorabid
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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