The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_471744 http://purl.obolibrary.org/obo/CHEBI_471744
Preferred Name	imipenem
Synonyms	(5R,6S)-3-(2-Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid imipenemum Imipenem Imipenem anhydrous (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(2-(iminomethylamino)ethylthio)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carbonsaeure (5R,6S)-3-({2-[(E)-(aminomethylidene)amino]ethyl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid C12H17N3O4S (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid N-formimidoylthienamycin N-formimidoyl thienamycin See more See less
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	imipenem
label	imipenem
DBSynonym	imipenem, n-formimidoyl thienamycin imp imipemide n-formimidoylthienamycin
Definition	A broad-spectrum, intravenous beta-lactam antibiotic of the carbapenem subgroup.
altId	CHEBI:5879
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2832 http://purl.obolibrary.org/obo/dinto_0081 http://purl.obolibrary.org/obo/dinto_3995 http://purl.obolibrary.org/obo/dinto_0360 http://purl.obolibrary.org/obo/dinto_1109
inhibits	http://purl.obolibrary.org/obo/dinto_2832 http://purl.obolibrary.org/obo/dinto_0081 http://purl.obolibrary.org/obo/dinto_3995 http://purl.obolibrary.org/obo/dinto_0360
type	http://www.w3.org/2002/07/owl#Class
has role	http://purl.obolibrary.org/obo/CHEBI_36047
InChIKey	InChIKey=ZSKVGTPCRGIANV-ZXFLCMHBSA-N
Synonym	(5R,6S)-3-(2-Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid imipenemum Imipenem Imipenem anhydrous (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(2-(iminomethylamino)ethylthio)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carbonsaeure (5R,6S)-3-({2-[(E)-(aminomethylidene)amino]ethyl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid C12H17N3O4S (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid N-formimidoylthienamycin N-formimidoyl thienamycin See more See less
xref	Wikipedia:http://en.wikipedia.org/wiki/Imipenem Patent:BE848545 KEGG DRUG:D04515 PubChem Substance:46505744 PubChem Compound:104838 ChEBI:471744 ChEMBL:143934 PharmGKB:PA449968 DrugBank:DB01598 CiteXplore:9131470 KEGG COMPOUND:C06665 Beilstein:434624 CiteXplore:1384868 Patent:US4194047 ChemSpider:94631 Drugs Product Database (DPD):717274 CiteXplore:2457043 CASRN:64221-86-9 See more See less
CASRN	74431-23-5
prefixIRI	obo2:CHEBI_471744
related with	http://purl.obolibrary.org/obo/dinto_1109
SMILES	[H][C@]12CC(SCC\N=C\N)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O [H]C(=N)NCCSC1=C(N2C(=O)[C@]([H])([C@@H](C)O)[C@@]2([H])C1)C(O)=O
may interact with	http://purl.obolibrary.org/obo/CHEBI_4031 http://purl.obolibrary.org/obo/CHEBI_63635
DBname	imipenem
InChI	InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1
DBBrand	tienamycin
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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