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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_4495
http://purl.obolibrary.org/obo/CHEBI_4495
|
|---|---|
| Preferred Name | diazoxide |
| Synonyms |
diazoxidum
7-chloro-3-methyl-4H-1$l^{6},2,4-benzothiadiazine-1,1-dione
Diazossido
Diazoxide
diazoxide
7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
diazoxido
C8H7ClN2O2S
Eudemine
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | diazoxide
|
|---|---|
| label | diazoxide
|
| ATCCode |
V03AH01
C02DA01
|
| Definition | A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
|
| altId | CHEBI:6046
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| has effect |
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| has pharmacological target | |
| induces | |
| inhibits | |
| type | |
| has role |
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| InChIKey | InChIKey=GDLBFKVLRPITMI-UHFFFAOYSA-N
|
| AHFScode | 24:08.20
|
| Synonym |
diazoxidum
7-chloro-3-methyl-4H-1$l^{6},2,4-benzothiadiazine-1,1-dione
Diazossido
Diazoxide
diazoxide
7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
diazoxido
C8H7ClN2O2S
Eudemine
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|
| xref |
Wikipedia:http://en.wikipedia.org/wiki/Diazoxide
CiteXplore:15319354
PubChem Compound:3019
CiteXplore:20828743
CiteXplore:20950601
ChEBI:4495
PubChem Substance:46508027
Beilstein:523907
CiteXplore:16777075
CiteXplore:16740260
ChemSpider:2911
CiteXplore:18191077
CiteXplore:21693179
National Drug Code Directory:0575-6000-01
Drugs Product Database (DPD):503347
Guide To Pharmacology:2409
Patent:DE723278
CASRN:364-98-7
ChEMBL:464859
DrugBank:DB01119
CiteXplore:22047130
CiteXplore:21538163
Reaxys:523907
KEGG COMPOUND:C06949
KEGG DRUG:D00294
Patent:US2986573
CiteXplore:12039709
Drugs.com:http://www.drugs.com/cdi/diazoxide-suspension.html
Patent:US3345365
IUPHAR:2409
PharmGKB:PA449285
Wikipedia:Diazoxide
CiteXplore:11014217
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| CASRN | 364-98-7
|
| prefixIRI | obo2:CHEBI_4495
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| related with | |
| SMILES |
CC1=NS(=O)(=O)C2=C(N1)C=CC(Cl)=C2
CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1
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| may interact with |
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| DBname | diazoxide
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| InChI | InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
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| DBBrand |
hypertonalum
mutabase
proglycem
proglicem
eudemine
hyperstat
dizoxide
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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