The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_44423 http://purl.obolibrary.org/obo/CHEBI_44423
Preferred Name	hydroxyurea
Synonyms	hydroxycarbamidum hydroxycarbamide Hydroxycarbamide Hydroxycarbamid N-carbamoylhydroxylamine Hydroxyurea N-HYDROXYUREA hydrea carbamoyl oxime CH4N2O2 carbamohydroxamic acid N-hydroxyurea oxyurea carbamohydroximic acid hidroxicarbamida Hydroxyharnstoff hydroxyurea carbamyl hydroxamate See more See less
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	hydroxyurea
label	hydroxyurea
DBSynonym	hydroxycarbamine hydroxycarbamide idrossicarbamide [dcit] hu carbamoyl oxime carbamohydroxamic acid hydroxicarbamidum carbamohydroximic acid hydroxylurea n-hydroxyurea carbamohydroxyamic acid n-carbamoylhydroxylamine carbamyl hydroxamate See more See less
ATCCode	L01XX05
Definition	A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease.
altId	CHEBI:5816 CHEBI:44420
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000557 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000267 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0001397 http://purl.obolibrary.org/obo/OAE_0001025 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0001365 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0001485 http://purl.obolibrary.org/obo/OAE_0001053 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000691 http://purl.obolibrary.org/obo/OAE_0000687 http://purl.obolibrary.org/obo/OAE_0000943 http://purl.obolibrary.org/obo/OAE_0001515 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0001341 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000752 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0001145 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000881 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0000716 http://purl.obolibrary.org/obo/OAE_0001364 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_1599
inhibits	http://purl.obolibrary.org/obo/dinto_1599 http://purl.obolibrary.org/obo/dinto_2993
type	http://www.w3.org/2002/07/owl#Class
has role	http://purl.obolibrary.org/obo/CHEBI_50905 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_50846 http://purl.obolibrary.org/obo/CHEBI_59517 http://purl.obolibrary.org/obo/CHEBI_35221 http://purl.obolibrary.org/obo/CHEBI_50902 http://purl.obolibrary.org/obo/CHEBI_64911 http://purl.obolibrary.org/obo/CHEBI_74213 http://purl.obolibrary.org/obo/CHEBI_48578 See more See less
InChIKey	InChIKey=VSNHCAURESNICA-UHFFFAOYSA-N
AHFScode	10:00.00
Synonym	hydroxycarbamidum hydroxycarbamide Hydroxycarbamide Hydroxycarbamid N-carbamoylhydroxylamine Hydroxyurea N-HYDROXYUREA hydrea carbamoyl oxime CH4N2O2 carbamohydroxamic acid N-hydroxyurea oxyurea carbamohydroximic acid hidroxicarbamida Hydroxyharnstoff hydroxyurea carbamyl hydroxamate See more See less
xref	CiteXplore:11285159 CiteXplore:11391710 CiteXplore:22983419 RxList:http://www.rxlist.com/cgi/generic2/hydroxyurea.htm HMDB:HMDB15140 PDBeChem:NHY CiteXplore:11298103 Drugs.com:http://www.drugs.com/cdi/hydroxyurea.html Wikipedia:http://en.wikipedia.org/wiki/Hydroxyurea CiteXplore:11365149 CiteXplore:15994344 CiteXplore:9271088 PubChem Substance:46506927 CiteXplore:15772364 CiteXplore:12107454 DrugBank:DB01005 KEGG DRUG:D00341 KEGG COMPOUND:C07044 PubChem Compound:3657 ChemSpider:3530 ChEMBL:104730 PharmGKB:PA449942 CiteXplore:23696560 Patent:US2705727 MetaCyc:HYDROXY-UREA CiteXplore:16356682 National Drug Code Directory:0555-0882-02 CiteXplore:14988684 CiteXplore:11364534 ChEBI:5816 Wikipedia:Hydroxyurea Drugs Product Database (DPD):2247937 CiteXplore:23318979 Gmelin:130423 CiteXplore:23643402 CASRN:1741548 CASRN:127-07-1 See more See less
CASRN	127-07-1
prefixIRI	obo2:CHEBI_44423
SMILES	NC(=O)NO
DBname	hydroxyurea
InChI	InChI=1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
DBBrand	hydurea hidrix litaler onco-carbide hydrea droxia hydura oxyurea hydreia biosupressin litalir ureaphil See more See less
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

Add comment

Add proposal

Subscribe to notes emails

Delete	Subject	Author	Type	Created
No notes to display