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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_439329
http://purl.obolibrary.org/obo/CHEBI_439329
|
|---|---|
| Preferred Name | (S)-fenfluramine |
| Synonyms |
dexfenfluramine
ethyl[(2S)-1-[3-(trifluoromethyl)phenyl]propan-2-yl]amine
(S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine
(S)-fenfluramine
dextrofenfluramine
(+)-fenfluramine
(2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine
dexfenfluramina
C12H16F3N
d-N-ethyl-alpha-methyl-m-trifluoromethylphenethylamine
dexfenfluraminum
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|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | (S)-fenfluramine
|
|---|---|
| label | (S)-fenfluramine
|
| DBSynonym |
dextrofenfluramine
(+)-fenfluramine
(s)-fenfluramine
|
| ATCCode | A08AA04
|
| Definition | The S-enantiomer of fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike fenfluramine it does not possess catecholamine agonist activity. It was formerly given by mouth as the hydrochloride in the treatment of obesity, but, like fenfluramine, was withdrawn wolrdwide following reports of valvular heart defects.
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| has pharmacological target | |
| activates | |
| inhibits |
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| type | |
| has role | |
| InChIKey | InChIKey=DBGIVFWFUFKIQN-VIFPVBQESA-N
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| is metabolised by | |
| Synonym |
dexfenfluramine
ethyl[(2S)-1-[3-(trifluoromethyl)phenyl]propan-2-yl]amine
(S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine
(S)-fenfluramine
dextrofenfluramine
(+)-fenfluramine
(2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine
dexfenfluramina
C12H16F3N
d-N-ethyl-alpha-methyl-m-trifluoromethylphenethylamine
dexfenfluraminum
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|
| xref |
PharmGKB:PA164747936
ChEBI:439329
DrugBank:DB01191
RxList:http://www.rxlist.com/cgi/generic/dexfen.htm
KEGG DRUG:D07805
Wikipedia:http://en.wikipedia.org/wiki/Dexfenfluramine
CASRN:3239-44-9
Patent:US3198834
Beilstein:4783710
ChEMBL:16257207
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| CASRN | 3239-44-9
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| prefixIRI | obo2:CHEBI_439329
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| SMILES |
CCN[C@@H](C)Cc1cccc(c1)C(F)(F)F
CCN[C@@H](C)CC1=CC=CC(=C1)C(F)(F)F
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| may interact with |
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| DBname | dexfenfluramine
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| InChI | InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m0/s1
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| DBBrand |
adifax
redux
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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