Link to this page
The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_4392
http://purl.obolibrary.org/obo/CHEBI_4392
|
|---|---|
| Preferred Name | demeclocycline |
| Synonyms |
DMCT
demeclocycline
demeclocyclinum
7-chloro-6-demethyltetracycline
[4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha)]-7-chloro-4-(dimethylamino)1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide
C21H21ClN2O8
demeclociclina
Demeclocycline
DMCTC
(4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
demethylchlortetracycline
6-demethyl-7-chlorotetracycline
See more
See less
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | demeclocycline
|
|---|---|
| label | demeclocycline
|
| DBSynonym |
demethylchlortetracyclin
demeclocyclinum [inn-latin]
demethylchlortetracyclinum
7-chloro-6-demethyltetracycline
methylchlorotetracycline
demeclocycline [usan:ban]
dmct
demethylchlorotetracycline
demeclociclina [inn-spanish]
tri-demethylchlortetracycline
6-demethylchlorotetracycline
demethylchlortetracycline
6-demethyl-7-chlorotetracycline
See more
See less
|
| ATCCode |
J01AA01
D06AA01
|
| Definition | Tetracycline which lacks the methyl substituent at position 7 and in which the hydrogen para- to the phenolic hydroxy group is substituted by chlorine. Like tetracycline, it is an antibiotic, but being excreted more slowly, effective blood levels are maintained for longer. It is used (mainly as the hydrochloride) for the treatment of Lyme disease, acne and bronchitis, as well as for hyponatraemia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective.
|
| altId | CHEBI:554084
|
| has effect |
See more
See less
|
| DBSalt |
demeclocycline hydrochloride
demeclocycline hcl
demethylchlortetracycline hydrochloride
|
| has pharmacological target | |
| inhibits | |
| type | |
| has role | |
| InChIKey | InChIKey=FMTDIUIBLCQGJB-SEYHBJAFSA-N
|
| AHFScode | 08:12.24
|
| Synonym | DMCT
demeclocycline
demeclocyclinum
7-chloro-6-demethyltetracycline
[4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha)]-7-chloro-4-(dimethylamino)1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide
C21H21ClN2O8
demeclociclina
Demeclocycline
DMCTC
(4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
demethylchlortetracycline
6-demethyl-7-chlorotetracycline
See more
See less
|
| xref |
Wikipedia:Demeclocycline
CASRN:127-33-3
DrugBank:DB00618
Patent:US2878289
Wikipedia:http://en.wikipedia.org/wiki/Demeclocycline
Patent:FR1344645
ChEBI:4392
RxList:http://www.rxlist.com/cgi/generic3/demeclocycline.htm
Drugs.com:http://www.drugs.com/cdi/demeclocycline.html
KEGG DRUG:D03680
Patent:US3019172
Patent:US3154476
National Drug Code Directory:61748-115-01
Beilstein:2230579
Patent:US3012946
PharmGKB:PA164745513
Patent:US3050446
Drugs Product Database (DPD):2169924
See more
See less
|
| CASRN | 127-33-3
|
| prefixIRI | obo2:CHEBI_4392
|
| SMILES |
[H][C@]12C[C@@]3([H])[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C1C(=O)C1=C([C@H]2O)C(Cl)=CC=C1O
[H][C@]12C[C@@]3([H])[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C1C(=O)c1c(O)ccc(Cl)c1[C@H]2O
|
| may interact with |
See more
See less
|
| DBname | demeclocycline
|
| InChI | InChI=1S/C21H21ClN2O8/c1-24(2)14-7-5-6-10(16(27)12-9(25)4-3-8(22)11(12)15(6)26)18(29)21(7,32)19(30)13(17(14)28)20(23)31/h3-4,6-7,14-15,25-26,28-29,32H,5H2,1-2H3,(H2,23,31)/t6-,7-,14-,15-,21-/m0/s1
|
| DBBrand |
diuciclin
mexocine
demeclor
elkamicina
bioterciclin
clortetrin
novotriclina
sumaclina
ledermycin
perciclina
deganol
declomycin
demetraclin
See more
See less
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |