The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Id	http://purl.obolibrary.org/obo/CHEBI_4325 http://purl.obolibrary.org/obo/CHEBI_4325
Preferred Name	dapsone
Synonyms	4-aminophenyl sulfone p,p-sulphonylbisbenzamine bis(4-aminophenyl)sulfone 4,4'-Sulfonylbisbenzenamine Bis(p-aminophenyl) sulfone p,p-sulphonylbisbenzenamine dapsone 4,4'-diaminodiphenyl sulfone 4-(4-aminophenylsulfonyl)aniline DIAPHENYLSULFONE 4-[(4-aminobenzene)sulfonyl]aniline p,p'-diaminodiphenyl sulfone 4-(4-aminophenylsulfonyl)benzenamine C12H12N2O2S dapsonum DADPS 4-(4-amino-benzenesulfonyl)-phenylamine dapsona DAPSONE DDS Dapsone 4,4'-sulfonylbisaniline 1,1'-sulfonylbis(4-aminobenzene) p-aminophenyl sulfone 4,4'-sulfonyldianiline Diaphenylsulfone 4,4'-dapsone See more See less
Type	http://www.w3.org/2002/07/owl#Class

prefLabel	dapsone
label	dapsone
DBSynonym	4,4'-diaminodiphenyl sulphone 4,4'-diaminodiphenyl sulfone 4,4'-diaminodiphenylsulfone 1,1'-sulfonylbis[4-aminobenzene] 4,4'-sulfonylbisbenzeneamine dds, pharmaceutical 4,4'-sulfonyldianiline 4,4'-sulfonyldianilin See more See less
ATCCode	J04BA02 D10AX05
Definition	Diphenylsulfone in which the hydrogen atom at the 4 position of each of the phenyl groups is substituted by an amino group. It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy.
altId	CHEBI:226356
has effect	http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000567 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0000333 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001433 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0001209 http://purl.obolibrary.org/obo/OAE_0001336 http://purl.obolibrary.org/obo/OAE_0000336 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0001054 See more See less
has pharmacological target	http://purl.obolibrary.org/obo/dinto_3133 http://purl.obolibrary.org/obo/dinto_3132
induces	http://purl.obolibrary.org/obo/dinto_2058
inhibits	http://purl.obolibrary.org/obo/dinto_3133 http://purl.obolibrary.org/obo/dinto_3132
type	http://www.w3.org/2002/07/owl#Class
has role	http://purl.obolibrary.org/obo/CHEBI_35441 http://purl.obolibrary.org/obo/CHEBI_35472 http://purl.obolibrary.org/obo/CHEBI_35816 http://purl.obolibrary.org/obo/CHEBI_38068
InChIKey	InChIKey=MQJKPEGWNLWLTK-UHFFFAOYSA-N
is metabolised by	http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_0293 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1956 http://purl.obolibrary.org/obo/dinto_1959 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_0938 http://purl.obolibrary.org/obo/dinto_0859 http://purl.obolibrary.org/obo/dinto_2116 http://purl.obolibrary.org/obo/dinto_2047 http://purl.obolibrary.org/obo/dinto_2048 See more See less
AHFScode	08:16.92
Synonym	4-aminophenyl sulfone p,p-sulphonylbisbenzamine bis(4-aminophenyl)sulfone 4,4'-Sulfonylbisbenzenamine Bis(p-aminophenyl) sulfone p,p-sulphonylbisbenzenamine dapsone 4,4'-diaminodiphenyl sulfone 4-(4-aminophenylsulfonyl)aniline DIAPHENYLSULFONE 4-[(4-aminobenzene)sulfonyl]aniline p,p'-diaminodiphenyl sulfone 4-(4-aminophenylsulfonyl)benzenamine C12H12N2O2S dapsonum DADPS 4-(4-amino-benzenesulfonyl)-phenylamine dapsona DAPSONE DDS Dapsone 4,4'-sulfonylbisaniline 1,1'-sulfonylbis(4-aminobenzene) p-aminophenyl sulfone 4,4'-sulfonyldianiline Diaphenylsulfone 4,4'-dapsone See more See less
xref	Patent:FR829926 KEGG COMPOUND:C07666 PubChem Substance:46505300 NIST Chemistry WebBook:80-08-0 BindingDB:50029764 CASRN:80-08-0 ChemSpider:2849 National Drug Code Directory:0469-5005-03 Wikipedia:Dapsone ChEBI:4325 Drugs.com:http://www.drugs.com/cdi/dapsone.html RxList:http://www.rxlist.com/cgi/generic/dapsone.htm Drugs Product Database (DPD):2041510 PharmGKB:PA449211 KEGG DRUG:D00592 Beilstein:788055 Wikipedia:http://en.wikipedia.org/wiki/Dapsone PubChem Compound:2955 DrugBank:DB00250 See more See less
CASRN	80-08-0
prefixIRI	obo2:CHEBI_4325
SMILES	NC1=CC=C(C=C1)S(=O)(=O)C1=CC=C(N)C=C1 Nc1ccc(cc1)S(=O)(=O)c1ccc(N)cc1
may interact with	http://purl.obolibrary.org/obo/CHEBI_156095 http://purl.obolibrary.org/obo/dinto_DB01370 http://purl.obolibrary.org/obo/CHEBI_31794 http://purl.obolibrary.org/obo/dinto_DB00582 http://purl.obolibrary.org/obo/dinto_DB01378 http://purl.obolibrary.org/obo/CHEBI_45367 http://purl.obolibrary.org/obo/dinto_DB00440 http://purl.obolibrary.org/obo/dinto_DB01373 http://purl.obolibrary.org/obo/CHEBI_27999 http://purl.obolibrary.org/obo/CHEBI_28077 http://purl.obolibrary.org/obo/dinto_DB00976 See more See less
DBname	dapsone
InChI	InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
DBBrand	aczone
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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