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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
| Id | http://purl.obolibrary.org/obo/CHEBI_408174
http://purl.obolibrary.org/obo/CHEBI_408174
|
|---|---|
| Preferred Name | arformoterol |
| Synonyms |
(-)-formoterol
C19H24N2O4
N-{2-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]phenyl}formamide
(R,R)-formoterol
arformoterol
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| prefLabel | arformoterol
|
|---|---|
| label | arformoterol
|
| DBSynonym | (r,r)-formoterol
|
| ATCCode | R03AC13
|
| Definition | An N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide in which both of the stereocentres have R configuration. The active enantiomer of formoterol, it is administered by inhalation (generally as the tartrate salt) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease (any progressive respiratory disease that makes it harder to breathe over time, such as chronic bronchitis and emphysema).
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| has pharmacological target | |
| activates | |
| type | |
| has role | |
| InChIKey | InChIKey=BPZSYCZIITTYBL-YJYMSZOUSA-N
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| is metabolised by | |
| AHFScode | 12:12.08.12
|
| Synonym |
(-)-formoterol
C19H24N2O4
N-{2-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]phenyl}formamide
(R,R)-formoterol
arformoterol
|
| xref |
Drugs.com:http://www.drugs.com/cdi/arformoterol.html
CASRN:67346-49-0
DrugBank:67346-49-0
BindingDB:50151720
RxList:http://www.rxlist.com/cgi/generic/brovana.htm
ChemSpider:2340731
DrugBank:DB01274
ChEMBL:15324892
PubChem Substance:46506392
PharmGKB:PA164743977
CiteXplore:20214460
CiteXplore:20406080
Beilstein:7861827
PubChem Compound:3083544
National Drug Code Directory:63402-911-30
ChEBI:408174
KEGG DRUG:D07463
CiteXplore:18990965
Patent:US2011014246
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| CASRN | 67346-49-0
|
| prefixIRI | obo2:CHEBI_408174
|
| SMILES |
[H]C(=O)Nc1cc(ccc1O)[C@@H](O)CN[C@H](C)Cc1ccc(OC)cc1
COC1=CC=C(C[C@@H](C)NC[C@H](O)C2=CC(NC=O)=C(O)C=C2)C=C1
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| DBname | arformoterol
|
| InChI | InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)/t13-,19+/m1/s1
|
| DBBrand | brovana
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |